Impact of Red Blood Cell Transfusion on Clinical Outcomes in Patients With Acute Myocardial Infarction

Doron Aronson, Eldad J. Dann, Lilach Bonstein, Miry Blich, Michael Kapeliovich, Rafael Beyar, Walter Markiewicz, Haim Hammerman

Research output: Contribution to journalArticle

Abstract

Divergent views remain regarding the safety of treating anemia with red blood cell (RBC) transfusion in patients with acute coronary syndrome (ACS). We used a prospective database to study effect of RBC transfusion in patients with acute myocardial infarction (MI; n = 2,358). Cox regression models were used to determine the association between RBC transfusion and 6-month outcomes, incorporating transfusion as a time-dependent variable. The models adjusted for baseline variables, propensity for transfusion, and nadir hemoglobin previous to the transfusion. One hundred ninety-two patients (8.1%) received RBC transfusion. Six-month mortality rates were higher in patients receiving transfusion (28.1% vs 11.7%, p 8 g/dL (adjusted HR 2.2, 95% CI 1.5 to 3.3; p

Original languageEnglish (US)
Pages (from-to)115-119
Number of pages5
JournalThe American Journal of Cardiology
Volume102
Issue number2
DOIs
StatePublished - Jul 15 2008
Externally publishedYes

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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