Impact of Red Blood Cell Transfusion on Clinical Outcomes in Patients With Acute Myocardial Infarction

Doron Aronson, Eldad J. Dann, Lilach Bonstein, Miry Blich, Michael Kapeliovich, Rafael Beyar, Walter Markiewicz, Haim Hammerman

Research output: Contribution to journalArticle

Abstract

Divergent views remain regarding the safety of treating anemia with red blood cell (RBC) transfusion in patients with acute coronary syndrome (ACS). We used a prospective database to study effect of RBC transfusion in patients with acute myocardial infarction (MI; n = 2,358). Cox regression models were used to determine the association between RBC transfusion and 6-month outcomes, incorporating transfusion as a time-dependent variable. The models adjusted for baseline variables, propensity for transfusion, and nadir hemoglobin previous to the transfusion. One hundred ninety-two patients (8.1%) received RBC transfusion. Six-month mortality rates were higher in patients receiving transfusion (28.1% vs 11.7%, p 8 g/dL (adjusted HR 2.2, 95% CI 1.5 to 3.3; p

Original languageEnglish (US)
Pages (from-to)115-119
Number of pages5
JournalThe American Journal of Cardiology
Volume102
Issue number2
DOIs
StatePublished - Jul 15 2008
Externally publishedYes

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Erythrocyte Transfusion
Myocardial Infarction
Acute Coronary Syndrome
Proportional Hazards Models
Anemia
Hemoglobins
Databases
Safety
Mortality

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Aronson, D., Dann, E. J., Bonstein, L., Blich, M., Kapeliovich, M., Beyar, R., ... Hammerman, H. (2008). Impact of Red Blood Cell Transfusion on Clinical Outcomes in Patients With Acute Myocardial Infarction. The American Journal of Cardiology, 102(2), 115-119. https://doi.org/10.1016/j.amjcard.2008.03.027

Impact of Red Blood Cell Transfusion on Clinical Outcomes in Patients With Acute Myocardial Infarction. / Aronson, Doron; Dann, Eldad J.; Bonstein, Lilach; Blich, Miry; Kapeliovich, Michael; Beyar, Rafael; Markiewicz, Walter; Hammerman, Haim.

In: The American Journal of Cardiology, Vol. 102, No. 2, 15.07.2008, p. 115-119.

Research output: Contribution to journalArticle

Aronson, D, Dann, EJ, Bonstein, L, Blich, M, Kapeliovich, M, Beyar, R, Markiewicz, W & Hammerman, H 2008, 'Impact of Red Blood Cell Transfusion on Clinical Outcomes in Patients With Acute Myocardial Infarction', The American Journal of Cardiology, vol. 102, no. 2, pp. 115-119. https://doi.org/10.1016/j.amjcard.2008.03.027
Aronson, Doron ; Dann, Eldad J. ; Bonstein, Lilach ; Blich, Miry ; Kapeliovich, Michael ; Beyar, Rafael ; Markiewicz, Walter ; Hammerman, Haim. / Impact of Red Blood Cell Transfusion on Clinical Outcomes in Patients With Acute Myocardial Infarction. In: The American Journal of Cardiology. 2008 ; Vol. 102, No. 2. pp. 115-119.
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