TY - JOUR
T1 - Impact of Red Blood Cell Transfusion on Clinical Outcomes in Patients With Acute Myocardial Infarction
AU - Aronson, Doron
AU - Dann, Eldad J.
AU - Bonstein, Lilach
AU - Blich, Miry
AU - Kapeliovich, Michael
AU - Beyar, Rafael
AU - Markiewicz, Walter
AU - Hammerman, Haim
PY - 2008/7/15
Y1 - 2008/7/15
N2 - Divergent views remain regarding the safety of treating anemia with red blood cell (RBC) transfusion in patients with acute coronary syndrome (ACS). We used a prospective database to study effect of RBC transfusion in patients with acute myocardial infarction (MI; n = 2,358). Cox regression models were used to determine the association between RBC transfusion and 6-month outcomes, incorporating transfusion as a time-dependent variable. The models adjusted for baseline variables, propensity for transfusion, and nadir hemoglobin previous to the transfusion. One hundred ninety-two patients (8.1%) received RBC transfusion. Six-month mortality rates were higher in patients receiving transfusion (28.1% vs 11.7%, p 8 g/dL (adjusted HR 2.2, 95% CI 1.5 to 3.3; p
AB - Divergent views remain regarding the safety of treating anemia with red blood cell (RBC) transfusion in patients with acute coronary syndrome (ACS). We used a prospective database to study effect of RBC transfusion in patients with acute myocardial infarction (MI; n = 2,358). Cox regression models were used to determine the association between RBC transfusion and 6-month outcomes, incorporating transfusion as a time-dependent variable. The models adjusted for baseline variables, propensity for transfusion, and nadir hemoglobin previous to the transfusion. One hundred ninety-two patients (8.1%) received RBC transfusion. Six-month mortality rates were higher in patients receiving transfusion (28.1% vs 11.7%, p 8 g/dL (adjusted HR 2.2, 95% CI 1.5 to 3.3; p
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U2 - 10.1016/j.amjcard.2008.03.027
DO - 10.1016/j.amjcard.2008.03.027
M3 - Article
C2 - 18602505
AN - SCOPUS:46349101720
SN - 0002-9149
VL - 102
SP - 115
EP - 119
JO - The American Journal of Cardiology
JF - The American Journal of Cardiology
IS - 2
ER -