Impact of metabolic complications on antiretroviral treatment adherence: Clinical and public health implications

Jean B. Nachega, Maria Paola Trotta, Mark Nelson, Adriana Ammassari

Research output: Contribution to journalReview article

Abstract

Antiretroviral therapy (ART) is an effective strategy for preventing disease progression of HIV infection, particularly when patients adhere closely to the treatment regimen. However, ART medications can cause side effects, including metabolic complications that can impact patients' adherence levels. Selected chronic complications associated with ART include lipodystrophy, hyperlipidemia, insulin resistance and diabetes, peripheral neuropathy, and bone disorders such as osteopenia/osteoporosis. In this article, we review the effects of these metabolic complications on ART adherence and approaches to prevent or reverse them

Original languageEnglish (US)
Pages (from-to)121-129
Number of pages9
JournalCurrent HIV/AIDS reports
Volume6
Issue number3
DOIs
StatePublished - Aug 1 2009

ASJC Scopus subject areas

  • Virology
  • Infectious Diseases

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