TY - JOUR
T1 - Impact of metabolic complications on antiretroviral treatment adherence
T2 - Clinical and public health implications
AU - Nachega, Jean B.
AU - Trotta, Maria Paola
AU - Nelson, Mark
AU - Ammassari, Adriana
N1 - Funding Information:
The authors would like to acknowledge Joanna Downer, PhD, for editorial support, and the following sources of financial support: Jean B. Nachega, MD, PhD—the National Institute of Allergy and Infectious Diseases, United States National Institutes of Health, Mentored Patient-Oriented Research Career Award K23 AI068582-01 and the Wellcome Trust’s Southern Africa Consortium for Research Excellence (SACORE): WT087537MA, London, United Kingdom.
PY - 2009/8
Y1 - 2009/8
N2 - Antiretroviral therapy (ART) is an effective strategy for preventing disease progression of HIV infection, particularly when patients adhere closely to the treatment regimen. However, ART medications can cause side effects, including metabolic complications that can impact patients' adherence levels. Selected chronic complications associated with ART include lipodystrophy, hyperlipidemia, insulin resistance and diabetes, peripheral neuropathy, and bone disorders such as osteopenia/osteoporosis. In this article, we review the effects of these metabolic complications on ART adherence and approaches to prevent or reverse them
AB - Antiretroviral therapy (ART) is an effective strategy for preventing disease progression of HIV infection, particularly when patients adhere closely to the treatment regimen. However, ART medications can cause side effects, including metabolic complications that can impact patients' adherence levels. Selected chronic complications associated with ART include lipodystrophy, hyperlipidemia, insulin resistance and diabetes, peripheral neuropathy, and bone disorders such as osteopenia/osteoporosis. In this article, we review the effects of these metabolic complications on ART adherence and approaches to prevent or reverse them
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U2 - 10.1007/s11904-009-0017-9
DO - 10.1007/s11904-009-0017-9
M3 - Review article
C2 - 19589297
AN - SCOPUS:67651246729
SN - 1548-3568
VL - 6
SP - 121
EP - 129
JO - Current HIV/AIDS reports
JF - Current HIV/AIDS reports
IS - 3
ER -