Impact of maternal characteristics on the effect of maternal influenza vaccination on fetal outcomes

Demilade A. Adedinsewo, Laila Noory, Robert A. Bednarczyk, Mark C. Steinhoff, Robert Davis, Chinelo Ogbuanu, Saad B. Omer

Research output: Contribution to journalArticle

Abstract

Background: Maternal infections during pregnancy have been associated with adverse fetal and infant health outcomes, and vaccination against influenza is the most effective tool to prevent morbidity and mortality due to seasonal and pandemic influenza. We evaluated the association between receipt of the inactivated seasonal influenza vaccine on preterm and small for gestational age (SGA) births, with the aim to assess racial and socioeconomic variations in vaccine effect. Methods: We conducted a retrospective analysis of state-wide surveillance data from Georgia for the most recent four years available at the beginning of the study, a total of 8393 live births in Georgia from January 1, 2005 through December 31, 2008. We constructed multivariable logistic regression models and calculated odds ratios (OR) estimates with corresponding 95% confidence intervals (CI) to evaluate the effect of maternal influenza vaccination on SGA (birth weight

Original languageEnglish (US)
Pages (from-to)5827-5833
Number of pages7
JournalVaccine
Volume31
Issue number49
DOIs
StatePublished - Dec 2 2013
Externally publishedYes

Fingerprint

maternal effect
influenza
Human Influenza
Vaccination
vaccination
Mothers
small for gestational age
Gestational Age
Logistic Models
Influenza Vaccines
Live Birth
Pandemics
vaccines
Birth Weight
pandemic
Vaccines
Odds Ratio
Parturition
birth weight
odds ratio

Keywords

  • Influenza
  • PRAMS
  • Pregnancy
  • Preterm birth
  • Small for gestational age
  • Vaccine

ASJC Scopus subject areas

  • Immunology and Microbiology(all)
  • Infectious Diseases
  • Public Health, Environmental and Occupational Health
  • veterinary(all)
  • Molecular Medicine

Cite this

Adedinsewo, D. A., Noory, L., Bednarczyk, R. A., Steinhoff, M. C., Davis, R., Ogbuanu, C., & Omer, S. B. (2013). Impact of maternal characteristics on the effect of maternal influenza vaccination on fetal outcomes. Vaccine, 31(49), 5827-5833. https://doi.org/10.1016/j.vaccine.2013.09.071

Impact of maternal characteristics on the effect of maternal influenza vaccination on fetal outcomes. / Adedinsewo, Demilade A.; Noory, Laila; Bednarczyk, Robert A.; Steinhoff, Mark C.; Davis, Robert; Ogbuanu, Chinelo; Omer, Saad B.

In: Vaccine, Vol. 31, No. 49, 02.12.2013, p. 5827-5833.

Research output: Contribution to journalArticle

Adedinsewo, DA, Noory, L, Bednarczyk, RA, Steinhoff, MC, Davis, R, Ogbuanu, C & Omer, SB 2013, 'Impact of maternal characteristics on the effect of maternal influenza vaccination on fetal outcomes', Vaccine, vol. 31, no. 49, pp. 5827-5833. https://doi.org/10.1016/j.vaccine.2013.09.071
Adedinsewo DA, Noory L, Bednarczyk RA, Steinhoff MC, Davis R, Ogbuanu C et al. Impact of maternal characteristics on the effect of maternal influenza vaccination on fetal outcomes. Vaccine. 2013 Dec 2;31(49):5827-5833. https://doi.org/10.1016/j.vaccine.2013.09.071
Adedinsewo, Demilade A. ; Noory, Laila ; Bednarczyk, Robert A. ; Steinhoff, Mark C. ; Davis, Robert ; Ogbuanu, Chinelo ; Omer, Saad B. / Impact of maternal characteristics on the effect of maternal influenza vaccination on fetal outcomes. In: Vaccine. 2013 ; Vol. 31, No. 49. pp. 5827-5833.
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