Impact of congenital cutaneous hemangiomas on newborn care in the United States

Raghav Tripathi, Rishabh S. Mazmudar, Konrad D. Knusel, Harib H. Ezaldein, Leah T. Belazarian, Jeremy S. Bordeaux, Jeffrey F. Scott

Research output: Contribution to journalArticlepeer-review


Little is known regarding the characteristics of newborns with congenital cutaneous hemangioma (CH) and the burden of CH on newborn care. The objective of this study is to describe the burden of CH on newborn inpatient stays in the United States. Specific aims include characterizing newborns with CH, assessing factors predictive of CH and procedures performed during hospitalization, determining characteristics associated with increased cost of care and length of stay in newborns with CH, and investigating trends in prevalence, length of stay, and cost of care. This is a nationally representative retrospective cohort study (National Inpatient Sample, 2009–2015). Sociodemographic factors associated with CH and risk factors for increased cost of care/length of stay were evaluated using weighted multivariable regression models. Overall prevalence of CH is 17.0 per 10,000 newborns. Cost of care and length of stay for newborns with CH are increasing over time. Controlling for all covariates, white (aOR 1.69), female (aOR 1.52) newborns from higher income families (aOR 1.44) were more likely to be born with CH (p < 0.001). Newborns with CH who were premature (aOR 3.88), underwent more procedures (aOR 8.81), and born in urban teaching hospitals (aOR 2.66) had the greatest cost of care (p < 0.001). Premature (aOR 3.74) newborns with CH in urban teaching hospitals (aOR 1.31) had the longest hospital stays (p < 0.001). The burden of CH in newborns is substantial and increasing over time. Understanding contributors to costly hospital stays is critical in developing evidence-based guidelines to reduce the growing impact of CH on newborn care.

Original languageEnglish (US)
Pages (from-to)641-651
Number of pages11
JournalArchives of Dermatological Research
Issue number8
StatePublished - Oct 2021


  • Cutaneous
  • Database
  • Economic burden
  • Financial
  • Guidelines
  • Hemangioma
  • Impact
  • Length of stay
  • National inpatient sample
  • Neonatal
  • Newborn
  • Premature
  • Screening

ASJC Scopus subject areas

  • Dermatology


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