Impact of Chlorhexidine Cord Cleansing on Mortality, Omphalitis and Cord Separation Time among Facility-Born Babies in Nepal and Bangladesh

Luke C. Mullany; Shams El Arifeen; Subarna K. Khatry; Joanne Katz; Rashed Shah; Abdullah H. Baqui; James M. Tielsch

doi:10.1097/INF.0000000000001617

Impact of Chlorhexidine Cord Cleansing on Mortality, Omphalitis and Cord Separation Time among Facility-Born Babies in Nepal and Bangladesh

Luke C. Mullany, Shams El Arifeen, Subarna K. Khatry, Joanne Katz, Rashed Shah, Abdullah H. Baqui, James M. Tielsch

Bloomberg School of Public Health

Research output: Contribution to journal › Review article › peer-review

Abstract

Guidance is needed regarding potential extension of the World Health Organization recommendation for cord cleansing with chlorhexidine to babies born in facilities. Among 3223 facility-born babies from Nepal and Bangladesh, mortality was approximately halved among those allocated to the intervention clusters [10.5/1000 vs. 19.4/1000; relative risk (RR): 0.54; 95% confidence interval: 0.30-0.97]. In high-mortality settings, a single policy for home and facility births is warranted.

Original language	English (US)
Pages (from-to)	1011-1013
Number of pages	3
Journal	Pediatric Infectious Disease Journal
Volume	36
Issue number	10
DOIs	https://doi.org/10.1097/INF.0000000000001617
State	Published - Oct 1 2017

Keywords

bacterial colonization
chlorhexidine
cord separation time
neonatal mortality
omphalitis
umbilical cord

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health
Microbiology (medical)
Infectious Diseases

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10.1097/INF.0000000000001617

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title = "Impact of Chlorhexidine Cord Cleansing on Mortality, Omphalitis and Cord Separation Time among Facility-Born Babies in Nepal and Bangladesh",

abstract = "Guidance is needed regarding potential extension of the World Health Organization recommendation for cord cleansing with chlorhexidine to babies born in facilities. Among 3223 facility-born babies from Nepal and Bangladesh, mortality was approximately halved among those allocated to the intervention clusters [10.5/1000 vs. 19.4/1000; relative risk (RR): 0.54; 95% confidence interval: 0.30-0.97]. In high-mortality settings, a single policy for home and facility births is warranted.",

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AU - Mullany, Luke C.

AU - Arifeen, Shams El

AU - Khatry, Subarna K.

AU - Katz, Joanne

AU - Shah, Rashed

AU - Baqui, Abdullah H.

AU - Tielsch, James M.

PY - 2017/10/1

Y1 - 2017/10/1

N2 - Guidance is needed regarding potential extension of the World Health Organization recommendation for cord cleansing with chlorhexidine to babies born in facilities. Among 3223 facility-born babies from Nepal and Bangladesh, mortality was approximately halved among those allocated to the intervention clusters [10.5/1000 vs. 19.4/1000; relative risk (RR): 0.54; 95% confidence interval: 0.30-0.97]. In high-mortality settings, a single policy for home and facility births is warranted.

AB - Guidance is needed regarding potential extension of the World Health Organization recommendation for cord cleansing with chlorhexidine to babies born in facilities. Among 3223 facility-born babies from Nepal and Bangladesh, mortality was approximately halved among those allocated to the intervention clusters [10.5/1000 vs. 19.4/1000; relative risk (RR): 0.54; 95% confidence interval: 0.30-0.97]. In high-mortality settings, a single policy for home and facility births is warranted.

KW - bacterial colonization

KW - chlorhexidine

KW - cord separation time

KW - neonatal mortality

KW - omphalitis

KW - umbilical cord

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Impact of Chlorhexidine Cord Cleansing on Mortality, Omphalitis and Cord Separation Time among Facility-Born Babies in Nepal and Bangladesh

Abstract

Keywords

ASJC Scopus subject areas

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