Impact of Body Mass Index on Biochemical Recurrence Rates After Radical Prostatectomy: An Analysis Utilizing Propensity Score Matching

Ahmed Magheli, Soroush Rais-Bahrami, Bruce Trock, Elizabeth B. Humphreys, Alan Wayne Partin, Misop Han, Mark L. Gonzalgo

Research output: Contribution to journalArticle

Abstract

Objectives: To investigate the significance of body mass index (BMI) as an independent predictor of biochemical recurrence in men treated with surgery for clinically localized adenocarcinoma of the prostate. Methods: A total of 1877 obese patients who underwent radical prostatectomy were matched to overweight and normal-weight patients in a 1:1 ratio on the basis of propensity scores. This resulted in an overall study population of 5631 men. Clinicopathologic characteristics and biochemical recurrence outcomes after surgery were compared between the three BMI cohorts. Results: Normal-weight patients exhibited lower-grade disease compared with overweight and obese patients (P = 0.021). Lower BMI was also significantly associated with lower rates of positive surgical margins (P

Original languageEnglish (US)
Pages (from-to)1246-1251
Number of pages6
JournalUrology
Volume72
Issue number6
DOIs
StatePublished - Dec 2008

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Propensity Score
Prostatectomy
Body Mass Index
Recurrence
Weights and Measures
Prostate
Adenocarcinoma
Population

ASJC Scopus subject areas

  • Urology

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Impact of Body Mass Index on Biochemical Recurrence Rates After Radical Prostatectomy : An Analysis Utilizing Propensity Score Matching. / Magheli, Ahmed; Rais-Bahrami, Soroush; Trock, Bruce; Humphreys, Elizabeth B.; Partin, Alan Wayne; Han, Misop; Gonzalgo, Mark L.

In: Urology, Vol. 72, No. 6, 12.2008, p. 1246-1251.

Research output: Contribution to journalArticle

Magheli, Ahmed ; Rais-Bahrami, Soroush ; Trock, Bruce ; Humphreys, Elizabeth B. ; Partin, Alan Wayne ; Han, Misop ; Gonzalgo, Mark L. / Impact of Body Mass Index on Biochemical Recurrence Rates After Radical Prostatectomy : An Analysis Utilizing Propensity Score Matching. In: Urology. 2008 ; Vol. 72, No. 6. pp. 1246-1251.
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