Immunology

David Moller; Muhunthan Thillai; Ajit Lalvani; Donald Mitchell

Immunology

David Moller, Muhunthan Thillai, Ajit Lalvani, Donald Mitchell

School of Medicine

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

The pathologic hallmark of sarcoidosis is discrete, compact non-caseating granulomas. The granulomas comprise mainly epithelioid cells with CD4 lymphocytes, mature macrophages and multinucleated giant cells interspersed throughout the epithelioid core and CD8 lymphocytes in the periphery. The granulomatous inflammation leads to distortion of local architecture, tissue injury and fibrosis.

Original language	English (US)
Title of host publication	Sarcoidosis
Publisher	CRC Press
Pages	48-59
Number of pages	12
ISBN (Electronic)	9781444149821
ISBN (Print)	9780340992111
State	Published - Jan 1 2012

ASJC Scopus subject areas

General Medicine

Cite this

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title = "Immunology",

abstract = "The pathologic hallmark of sarcoidosis is discrete, compact non-caseating granulomas. The granulomas comprise mainly epithelioid cells with CD4 lymphocytes, mature macrophages and multinucleated giant cells interspersed throughout the epithelioid core and CD8 lymphocytes in the periphery. The granulomatous inflammation leads to distortion of local architecture, tissue injury and fibrosis.",

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TY - CHAP

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AU - Moller, David

AU - Thillai, Muhunthan

AU - Lalvani, Ajit

AU - Mitchell, Donald

PY - 2012/1/1

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N2 - The pathologic hallmark of sarcoidosis is discrete, compact non-caseating granulomas. The granulomas comprise mainly epithelioid cells with CD4 lymphocytes, mature macrophages and multinucleated giant cells interspersed throughout the epithelioid core and CD8 lymphocytes in the periphery. The granulomatous inflammation leads to distortion of local architecture, tissue injury and fibrosis.

AB - The pathologic hallmark of sarcoidosis is discrete, compact non-caseating granulomas. The granulomas comprise mainly epithelioid cells with CD4 lymphocytes, mature macrophages and multinucleated giant cells interspersed throughout the epithelioid core and CD8 lymphocytes in the periphery. The granulomatous inflammation leads to distortion of local architecture, tissue injury and fibrosis.

UR - http://www.scopus.com/inward/record.url?scp=85055215941&partnerID=8YFLogxK

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M3 - Chapter

AN - SCOPUS:85055215941

SN - 9780340992111

SP - 48

EP - 59

BT - Sarcoidosis

PB - CRC Press

ER -

Immunology

Abstract

ASJC Scopus subject areas

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