Immunological ignorance of silent antigens as an explanation of tumor evasion

Lieping Chen

Research output: Contribution to journalArticle

Abstract

Although there is little doubt about the existence of tumor antigens that can be recognized by cytotoxic T lymphocytes in common human cancers, it is still unclear why these antigens do not cause tumor rejection. Here, Lieping Chen proposes that immunological ignorance of silent antigens might explain the inefficient T-cell response to cancer, and suggests how this may be overcome.

Original languageEnglish (US)
Pages (from-to)27-30
Number of pages4
JournalImmunology Today
Volume19
Issue number1
DOIs
StatePublished - Jan 1998
Externally publishedYes

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Antigens
Neoplasms
Cytotoxic T-Lymphocytes
Neoplasm Antigens
T-Lymphocytes

ASJC Scopus subject areas

  • Immunology

Cite this

Immunological ignorance of silent antigens as an explanation of tumor evasion. / Chen, Lieping.

In: Immunology Today, Vol. 19, No. 1, 01.1998, p. 27-30.

Research output: Contribution to journalArticle

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