Abstract
The immunologic status of 18 Old Order Amish persons with cartilage-hair hypoplasia and 9 unaffected sibs was studied. Although none of the subjects had a history suggestive of persistent immune dysfunction, the subjects with cartilage-hair hypoplasia had significantly lower lymphocyte mitogenic and allogeneic cell stimulation responses when compared to unaffected sibs and unrelated control subjects. The abnormalities of cellular immune function found in the 18 affected subjects were similar to those reported in Finnish subjects with cartilage-hair hypoplasia.
Original language | English (US) |
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Pages (from-to) | 157-164 |
Number of pages | 8 |
Journal | Johns Hopkins Medical Journal |
Volume | 148 |
Issue number | 4 |
State | Published - 1981 |
ASJC Scopus subject areas
- General Medicine