Immunologic implications of vasectomy: I. Cell mediated immunity

G. E. Brannen, A. M. Kwart, D. S. Coffey

Research output: Contribution to journalArticle

Abstract

Thirty male Lewis rats underwent vasectomy with ligation of the vas deferens, vasectomy without ligation of the vas deferens, and sham vasectomy in groups of 10. Assays for cell mediated immunity were performed with each experimental group 90 days after operative procedure. Three specific tests were utilized to demonstrate cell mediated immunity specific to syngeneic spermatozoa. The 3 tests were: footpad swelling response to the injection of syngeneic spermatozoa; release of radioactivity from 51chromium labeled spermatozoa; and release of macrophage migration inhibition factor by lymphocytes incubated with spermatozoa. Cell mediated immunity was present only in rats without ligation of the vas deferens.

Original languageEnglish (US)
Pages (from-to)508-514
Number of pages7
JournalFertility and Sterility
Volume25
Issue number6
StatePublished - 1974

Fingerprint

Vasectomy
Cellular Immunity
Vas Deferens
Spermatozoa
Ligation
Macrophage Migration-Inhibitory Factors
Operative Surgical Procedures
Radioactivity
Lymphocytes
Injections

ASJC Scopus subject areas

  • Obstetrics and Gynecology

Cite this

Brannen, G. E., Kwart, A. M., & Coffey, D. S. (1974). Immunologic implications of vasectomy: I. Cell mediated immunity. Fertility and Sterility, 25(6), 508-514.

Immunologic implications of vasectomy : I. Cell mediated immunity. / Brannen, G. E.; Kwart, A. M.; Coffey, D. S.

In: Fertility and Sterility, Vol. 25, No. 6, 1974, p. 508-514.

Research output: Contribution to journalArticle

Brannen, GE, Kwart, AM & Coffey, DS 1974, 'Immunologic implications of vasectomy: I. Cell mediated immunity', Fertility and Sterility, vol. 25, no. 6, pp. 508-514.
Brannen, G. E. ; Kwart, A. M. ; Coffey, D. S. / Immunologic implications of vasectomy : I. Cell mediated immunity. In: Fertility and Sterility. 1974 ; Vol. 25, No. 6. pp. 508-514.
@article{d92317177082445cb7d4d4af81e3145f,
title = "Immunologic implications of vasectomy: I. Cell mediated immunity",
abstract = "Thirty male Lewis rats underwent vasectomy with ligation of the vas deferens, vasectomy without ligation of the vas deferens, and sham vasectomy in groups of 10. Assays for cell mediated immunity were performed with each experimental group 90 days after operative procedure. Three specific tests were utilized to demonstrate cell mediated immunity specific to syngeneic spermatozoa. The 3 tests were: footpad swelling response to the injection of syngeneic spermatozoa; release of radioactivity from 51chromium labeled spermatozoa; and release of macrophage migration inhibition factor by lymphocytes incubated with spermatozoa. Cell mediated immunity was present only in rats without ligation of the vas deferens.",
author = "Brannen, {G. E.} and Kwart, {A. M.} and Coffey, {D. S.}",
year = "1974",
language = "English (US)",
volume = "25",
pages = "508--514",
journal = "Fertility and Sterility",
issn = "0015-0282",
publisher = "Elsevier Inc.",
number = "6",

}

TY - JOUR

T1 - Immunologic implications of vasectomy

T2 - I. Cell mediated immunity

AU - Brannen, G. E.

AU - Kwart, A. M.

AU - Coffey, D. S.

PY - 1974

Y1 - 1974

N2 - Thirty male Lewis rats underwent vasectomy with ligation of the vas deferens, vasectomy without ligation of the vas deferens, and sham vasectomy in groups of 10. Assays for cell mediated immunity were performed with each experimental group 90 days after operative procedure. Three specific tests were utilized to demonstrate cell mediated immunity specific to syngeneic spermatozoa. The 3 tests were: footpad swelling response to the injection of syngeneic spermatozoa; release of radioactivity from 51chromium labeled spermatozoa; and release of macrophage migration inhibition factor by lymphocytes incubated with spermatozoa. Cell mediated immunity was present only in rats without ligation of the vas deferens.

AB - Thirty male Lewis rats underwent vasectomy with ligation of the vas deferens, vasectomy without ligation of the vas deferens, and sham vasectomy in groups of 10. Assays for cell mediated immunity were performed with each experimental group 90 days after operative procedure. Three specific tests were utilized to demonstrate cell mediated immunity specific to syngeneic spermatozoa. The 3 tests were: footpad swelling response to the injection of syngeneic spermatozoa; release of radioactivity from 51chromium labeled spermatozoa; and release of macrophage migration inhibition factor by lymphocytes incubated with spermatozoa. Cell mediated immunity was present only in rats without ligation of the vas deferens.

UR - http://www.scopus.com/inward/record.url?scp=0016171379&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0016171379&partnerID=8YFLogxK

M3 - Article

C2 - 4835606

AN - SCOPUS:0016171379

VL - 25

SP - 508

EP - 514

JO - Fertility and Sterility

JF - Fertility and Sterility

SN - 0015-0282

IS - 6

ER -