Immunodeficiency and elevated CD4 T lymphocyte counts in two patients coinfected with human immunodeficiency virus and human lymphotropic virus type I

Lori Fantry, Eric De Jonge, Paul G Auwaerter, Howard M Lederman

Research output: Contribution to journalArticle

Abstract

We describe two patients who were coinfected with human immunodeficiency virus (HIV) and human T-cell lymphotropic virus (HTLV) type I. They had clinical evidence of immunodeficiency (anergy, oral candidiasis, and disseminated herpes zoster) despite having elevated CD4 T lymphocyte counts (range, 2,450-5,292/mm3). We conclude that CD4 lymphocyte counts may not be reliable markers of immunologic competence in patients coinfected with HIV and HTLV-I.

Original languageEnglish (US)
Pages (from-to)1466-1468
Number of pages3
JournalClinical Infectious Diseases
Volume21
Issue number6
StatePublished - 1995

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CD4 Lymphocyte Count
HIV
Viruses
T-Lymphocytes
Oral Candidiasis
Immunocompetence
Herpes Zoster

ASJC Scopus subject areas

  • Immunology

Cite this

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abstract = "We describe two patients who were coinfected with human immunodeficiency virus (HIV) and human T-cell lymphotropic virus (HTLV) type I. They had clinical evidence of immunodeficiency (anergy, oral candidiasis, and disseminated herpes zoster) despite having elevated CD4 T lymphocyte counts (range, 2,450-5,292/mm3). We conclude that CD4 lymphocyte counts may not be reliable markers of immunologic competence in patients coinfected with HIV and HTLV-I.",
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