Immunocytochemical Localization of Cathepsin D in Rabbit Skin

Gerald Sylvan Lazarus, A. Robin Poole

Research output: Contribution to journalArticle

Abstract

The lysosomal proteinase cathepsin D has been localized in rabbit skin by immunocytochemical techniques. The enzyme was found in the basal layer of the epidermis, hair follicles, sebaceous glands, fibroblasts, and endothelial cells. An autoradiographic technique, using the Fab' fragment of IgG, was also used for more effective identification of cell types that contain cathepsin D.

Original languageEnglish (US)
Pages (from-to)1150-1153
Number of pages4
JournalArchives of Dermatology
Volume111
Issue number9
DOIs
StatePublished - 1975
Externally publishedYes

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Cathepsin D
Rabbits
Sebaceous Glands
Skin
Immunoglobulin Fab Fragments
Hair Follicle
Epidermis
Endothelial Cells
Fibroblasts
Immunoglobulin G
Enzymes
proteinase D

ASJC Scopus subject areas

  • Dermatology

Cite this

Immunocytochemical Localization of Cathepsin D in Rabbit Skin. / Lazarus, Gerald Sylvan; Poole, A. Robin.

In: Archives of Dermatology, Vol. 111, No. 9, 1975, p. 1150-1153.

Research output: Contribution to journalArticle

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