Immunocytochemical Localization of Cathepsin D in Rabbit Skin

Gerald S. Lazarus, A. Robin Poole

Research output: Contribution to journalArticlepeer-review

15 Scopus citations


The lysosomal proteinase cathepsin D has been localized in rabbit skin by immunocytochemical techniques. The enzyme was found in the basal layer of the epidermis, hair follicles, sebaceous glands, fibroblasts, and endothelial cells. An autoradiographic technique, using the Fab' fragment of IgG, was also used for more effective identification of cell types that contain cathepsin D.

Original languageEnglish (US)
Pages (from-to)1150-1153
Number of pages4
JournalArchives of Dermatology
Issue number9
StatePublished - Sep 1975
Externally publishedYes

ASJC Scopus subject areas

  • Dermatology


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