Immunochemical studies of prostatic acid phosphatase

B. K. Choe, E. J. Pontes, I. McDonald, N. R. Rose

Research output: Contribution to journalArticlepeer-review

35 Scopus citations


Immunologic specificity of the prostatic acid phosphatase (PAP) and the kinetics of the PAP-anti-PAP antibody interactions were studied in detail. Antigenic identity of electrophoretic isozymes of PAP was established in this study. Counter-immunoelectrophoretic assay, radioimmunoassay, and immunofluorescence technique were developed to detect PAP and PAP-synthesizing cells. These techniques were applied to the determination of serum PAP levels and to the identification of metastatic prostate cancer cells in biopsies.

Original languageEnglish (US)
Pages (from-to)201-204
Number of pages4
JournalCancer treatment reports
Issue number2
StatePublished - Dec 1 1977

ASJC Scopus subject areas

  • Oncology
  • Cancer Research


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