Immune system reconstitution following allogeneic bone marrow transplantation in man: a multiparameter analysis

G. J. Elfenbein, P. N. Anderson, R. L. Humphrey, G. M. Mullins, L. L. Sensenbrenner, J. R. Wands, G. W. Santos

Research output: Contribution to journalReview article

Abstract

In order to define more precisely the immunodeficiency that occurs following allogeneic BMT in man and to elucidate in more detail the events occurring during the period of immune system recovery, humoral and cellular immunity both in vivo and in vitro have been studied in the 25 patients at the center who survived 2 or more months following allogeneic BMT. An interesting combined immunodeficiency (CID) was observed. The kinetics of recovery from the CID showed a dissociation between the various lymphocyte surface markers, products, and functions that were measured.

Original languageEnglish (US)
Pages (from-to)641-646
Number of pages6
JournalTransplantation proceedings
Volume8
Issue number4
StatePublished - Dec 1 1976

ASJC Scopus subject areas

  • Surgery
  • Transplantation

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    Elfenbein, G. J., Anderson, P. N., Humphrey, R. L., Mullins, G. M., Sensenbrenner, L. L., Wands, J. R., & Santos, G. W. (1976). Immune system reconstitution following allogeneic bone marrow transplantation in man: a multiparameter analysis. Transplantation proceedings, 8(4), 641-646.