Immune response to rotaviral infection - measurement by enzyme immunoassay

R. H. Yolken, B. A. Barbour, R. G. Wyatt, A. Z. Kapikian

Research output: Contribution to journalArticlepeer-review

4 Scopus citations

Abstract

The results by enzyme immunoassay (ELISA) were comparable with those of fluorescent antibody and complement-fixation techniques, except that titers determined by ELISA were higher. In addition, ELISA was more sensitive in detecting antibody responses in sera from infected children who were less than 6 months of age and who did not demonstrate seroconversion values when tested by complement fixation. In addition, ELISA was more sensitive than complement fixation in detecting antibody response in adult contacts of children who had gastrointestinal infection and in adult volunteers experimentally infected with rotavirus.

Original languageEnglish (US)
Pages (from-to)552-554
Number of pages3
JournalJournal of the American Veterinary Medical Association
Volume173
Issue number5 II
StatePublished - Jan 1 1978
Externally publishedYes

ASJC Scopus subject areas

  • General Veterinary

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