Immune-mediated clearance of virus from the central nervous system

Gwendolyn K. Binder, Diane E. Griffin

Research output: Contribution to journalReview articlepeer-review

Abstract

Immune-mediated clearance of virus from the central nervous system (CNS) differs from that of the other organs. Mechanisms of virus control are largely dependent upon the target cell type. Although cytolytic T lymphocytes may mediate clearance of virus from glial cells, non-cytolytic mechanisms mediated by antibody and cytokines dominate clearance from neurons.

Original languageEnglish (US)
Pages (from-to)439-448
Number of pages10
JournalMicrobes and Infection
Volume5
Issue number5
DOIs
StatePublished - Apr 2003

Keywords

  • Central nervous system
  • Immune system
  • Virus replication

ASJC Scopus subject areas

  • Microbiology
  • Immunology
  • Infectious Diseases

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