Abstract
The ability to non-invasively measure neurotransmitter receptors in man by emission computed tomography has the potential to (1) improve understanding of the biochemical basis of neurodegenerative and psychiatric disorders; (2) monitor drug action by directly measuring changes in receptor occupancy; and (3) lead to improved knowledge of the physiology of neurotransmitter systems by monitoring changes in receptor occupancy as a result of altered neurotransmitter release. James Frost describes selective ligands currenly available to image neuroreceptors and their subtypes and their use in elucidating biochemical events in health and disease.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 490-496 |
| Number of pages | 7 |
| Journal | Trends in Pharmacological Sciences |
| Volume | 7 |
| Issue number | C |
| DOIs | |
| State | Published - 1986 |
ASJC Scopus subject areas
- Pharmacology
- Toxicology