Imaging microvascular obstruction and its clinical significance following acute myocardial infarction

Albert K. Luo, Katherine C. Wu

Research output: Contribution to journalArticle

Abstract

Obstruction of the coronary microvasculature contributes to the pathophysiology of MI and adversely affects post-MI recovery. This no-reflow phenomenon resulting from microvascular obstruction is an indicator of lack of adequate tissue perfusion within the infarcted myocardium, even after restoration of epicardial blood flow. Regions of microvascular obstruction can be detected and quantifed because of rapid advances in and refinement of imaging technologies over the past decade. This article focuses on the non-invasive imaging modalities used to assess MO, discusses the prognostic implications of MO, and briefly addresses strategies for reducing MO.

Original languageEnglish (US)
Pages (from-to)305-312
Number of pages8
JournalHeart Failure Reviews
Volume11
Issue number4
DOIs
StatePublished - Dec 1 2006

Keywords

  • Microvascular obstruction (MO)
  • No-reflow
  • Post-MI prognosis

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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