TY - JOUR
T1 - Imaging Macrophage-associated Inflammation
AU - Foss, Catherine A.
AU - Sanchez-Bautista, Julian
AU - Jain, Sanjay K.
N1 - Funding Information:
This work was supported by the National Institutes of Health Director's Transformative Research Award R01-EB020539 (S.K.J.) and R01- HL131829 (S.K.J.). The funders had no role in the study design, data collection and analysis, decision to publish, or preparation of the manuscript.
Publisher Copyright:
© 2017
PY - 2018/5
Y1 - 2018/5
N2 - Macrophages belong to the mononuclear phagocyte system comprising closely related cells of bone marrow origin. Activated macrophages are critical in several diseases such as tuberculosis, sarcoidosis, Crohn's disease, and atherosclerosis. Noninvasive imaging techniques that can specifically image activated macrophages could therefore help in differentiating various forms of inflammatory diseases and to monitor therapeutic responses.
AB - Macrophages belong to the mononuclear phagocyte system comprising closely related cells of bone marrow origin. Activated macrophages are critical in several diseases such as tuberculosis, sarcoidosis, Crohn's disease, and atherosclerosis. Noninvasive imaging techniques that can specifically image activated macrophages could therefore help in differentiating various forms of inflammatory diseases and to monitor therapeutic responses.
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U2 - 10.1053/j.semnuclmed.2017.12.002
DO - 10.1053/j.semnuclmed.2017.12.002
M3 - Review article
C2 - 29626941
AN - SCOPUS:85041955661
SN - 0001-2998
VL - 48
SP - 242
EP - 245
JO - Seminars in Nuclear Medicine
JF - Seminars in Nuclear Medicine
IS - 3
ER -