Imaging brain tumor by dendrimer-based optical/paramagnetic nanoprobe across the blood-brain barrier

Huihui Yan; Jiyao Wang; Peiwei Yi; Hao Lei; Changyou Zhan; Cao Xie; Linglin Feng; Jun Qian; Jianhua Zhu; Weiyue Lu; Cong Li

doi:10.1039/c1cc12007g

Imaging brain tumor by dendrimer-based optical/paramagnetic nanoprobe across the blood-brain barrier

Huihui Yan, Jiyao Wang, Peiwei Yi, Hao Lei, Changyou Zhan, Cao Xie, Linglin Feng, Jun Qian, Jianhua Zhu, Weiyue Lu, Cong Li

Research output: Contribution to journal › Article › peer-review

60 Scopus citations

Abstract

A multimodal optical/paramagnetic nanoprobe, Den-Angio, was developed and demonstrated a capability to circumvent the blood brain barrier (BBB) and visualize brain tumors with high sensitivity in vivo. Den-Angio holds promise to pre-operatively localize brain tumors and make image-guided tumor resection possible during surgery.

Original language	English (US)
Pages (from-to)	8130-8132
Number of pages	3
Journal	Chemical Communications
Volume	47
Issue number	28
DOIs	https://doi.org/10.1039/c1cc12007g
State	Published - Jul 28 2011
Externally published	Yes

ASJC Scopus subject areas

Metals and Alloys
Materials Chemistry
Surfaces, Coatings and Films
Electronic, Optical and Magnetic Materials
Ceramics and Composites
Catalysis
Chemistry(all)

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10.1039/c1cc12007g

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title = "Imaging brain tumor by dendrimer-based optical/paramagnetic nanoprobe across the blood-brain barrier",

abstract = "A multimodal optical/paramagnetic nanoprobe, Den-Angio, was developed and demonstrated a capability to circumvent the blood brain barrier (BBB) and visualize brain tumors with high sensitivity in vivo. Den-Angio holds promise to pre-operatively localize brain tumors and make image-guided tumor resection possible during surgery.",

author = "Huihui Yan and Jiyao Wang and Peiwei Yi and Hao Lei and Changyou Zhan and Cao Xie and Linglin Feng and Jun Qian and Jianhua Zhu and Weiyue Lu and Cong Li",

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doi = "10.1039/c1cc12007g",

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T1 - Imaging brain tumor by dendrimer-based optical/paramagnetic nanoprobe across the blood-brain barrier

AU - Yan, Huihui

AU - Wang, Jiyao

AU - Yi, Peiwei

AU - Lei, Hao

AU - Zhan, Changyou

AU - Xie, Cao

AU - Feng, Linglin

AU - Qian, Jun

AU - Zhu, Jianhua

AU - Lu, Weiyue

AU - Li, Cong

PY - 2011/7/28

Y1 - 2011/7/28

N2 - A multimodal optical/paramagnetic nanoprobe, Den-Angio, was developed and demonstrated a capability to circumvent the blood brain barrier (BBB) and visualize brain tumors with high sensitivity in vivo. Den-Angio holds promise to pre-operatively localize brain tumors and make image-guided tumor resection possible during surgery.

AB - A multimodal optical/paramagnetic nanoprobe, Den-Angio, was developed and demonstrated a capability to circumvent the blood brain barrier (BBB) and visualize brain tumors with high sensitivity in vivo. Den-Angio holds promise to pre-operatively localize brain tumors and make image-guided tumor resection possible during surgery.

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DO - 10.1039/c1cc12007g

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JF - Chemical Communications

SN - 1359-7345

IS - 28

ER -

Imaging brain tumor by dendrimer-based optical/paramagnetic nanoprobe across the blood-brain barrier

Abstract

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