Imaging brain tumor by dendrimer-based optical/paramagnetic nanoprobe across the blood-brain barrier

Huihui Yan, Jiyao Wang, Peiwei Yi, Hao Lei, Changyou Zhan, Cao Xie, Linglin Feng, Jun Qian, Jianhua Zhu, Weiyue Lu, Cong Li

Research output: Contribution to journalArticlepeer-review

Abstract

A multimodal optical/paramagnetic nanoprobe, Den-Angio, was developed and demonstrated a capability to circumvent the blood brain barrier (BBB) and visualize brain tumors with high sensitivity in vivo. Den-Angio holds promise to pre-operatively localize brain tumors and make image-guided tumor resection possible during surgery.

Original languageEnglish (US)
Pages (from-to)8130-8132
Number of pages3
JournalChemical Communications
Volume47
Issue number28
DOIs
StatePublished - Jul 28 2011
Externally publishedYes

ASJC Scopus subject areas

  • Metals and Alloys
  • Materials Chemistry
  • Surfaces, Coatings and Films
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Catalysis
  • Chemistry(all)

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