Imaging brain tumor by dendrimer-based optical/paramagnetic nanoprobe across the blood-brain barrier

Huihui Yan; Jiyao Wang; Peiwei Yi; Hao Lei; Changyou Zhan; Cao Xie; Linglin Feng; Jun Qian; Jianhua Zhu; Weiyue Lu; Cong Li

doi:10.1039/c1cc12007g

Imaging brain tumor by dendrimer-based optical/paramagnetic nanoprobe across the blood-brain barrier

Huihui Yan, Jiyao Wang, Peiwei Yi, Hao Lei, Changyou Zhan, Cao Xie, Linglin Feng, Jun Qian, Jianhua Zhu, Weiyue Lu, Cong Li

Research output: Contribution to journal › Article › peer-review

Abstract

A multimodal optical/paramagnetic nanoprobe, Den-Angio, was developed and demonstrated a capability to circumvent the blood brain barrier (BBB) and visualize brain tumors with high sensitivity in vivo. Den-Angio holds promise to pre-operatively localize brain tumors and make image-guided tumor resection possible during surgery.

Original language	English (US)
Pages (from-to)	8130-8132
Number of pages	3
Journal	Chemical Communications
Volume	47
Issue number	28
DOIs	https://doi.org/10.1039/c1cc12007g
State	Published - Jul 28 2011
Externally published	Yes

ASJC Scopus subject areas

Metals and Alloys
Materials Chemistry
Surfaces, Coatings and Films
Electronic, Optical and Magnetic Materials
Ceramics and Composites
Catalysis
Chemistry(all)

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10.1039/c1cc12007g

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Imaging brain tumor by dendrimer-based optical/paramagnetic nanoprobe across the blood-brain barrier. / Yan, Huihui; Wang, Jiyao; Yi, Peiwei; Lei, Hao; Zhan, Changyou; Xie, Cao; Feng, Linglin; Qian, Jun; Zhu, Jianhua; Lu, Weiyue; Li, Cong.

In: Chemical Communications, Vol. 47, No. 28, 28.07.2011, p. 8130-8132.

Research output: Contribution to journal › Article › peer-review

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abstract = "A multimodal optical/paramagnetic nanoprobe, Den-Angio, was developed and demonstrated a capability to circumvent the blood brain barrier (BBB) and visualize brain tumors with high sensitivity in vivo. Den-Angio holds promise to pre-operatively localize brain tumors and make image-guided tumor resection possible during surgery.",

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AU - Yan, Huihui

AU - Wang, Jiyao

AU - Yi, Peiwei

AU - Lei, Hao

AU - Zhan, Changyou

AU - Xie, Cao

AU - Feng, Linglin

AU - Qian, Jun

AU - Zhu, Jianhua

AU - Lu, Weiyue

AU - Li, Cong

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AB - A multimodal optical/paramagnetic nanoprobe, Den-Angio, was developed and demonstrated a capability to circumvent the blood brain barrier (BBB) and visualize brain tumors with high sensitivity in vivo. Den-Angio holds promise to pre-operatively localize brain tumors and make image-guided tumor resection possible during surgery.

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Imaging brain tumor by dendrimer-based optical/paramagnetic nanoprobe across the blood-brain barrier

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