TY - JOUR
T1 - Imaging and Data Acquisition in Clinical Trials for Radiation Therapy
AU - Fitzgerald, Thomas J.
AU - Bishop-Jodoin, Maryann
AU - Followill, David S.
AU - Galvin, James
AU - Knopp, Michael V.
AU - Michalski, Jeff M.
AU - Rosen, Mark A.
AU - Bradley, Jeffrey D.
AU - Shankar, Lalitha K.
AU - Laurie, Fran
AU - Cicchetti, M. Giulia
AU - Moni, Janaki
AU - Coleman, C. Norman
AU - Deye, James A.
AU - Capala, Jacek
AU - Vikram, Bhadrasain
N1 - Publisher Copyright:
© 2016 Elsevier Inc.
PY - 2016/2/1
Y1 - 2016/2/1
N2 - Cancer treatment evolves through oncology clinical trials. Cancer trials are multimodal and complex. Assuring high-quality data are available to answer not only study objectives but also questions not anticipated at study initiation is the role of quality assurance. The National Cancer Institute reorganized its cancer clinical trials program in 2014. The National Clinical Trials Network (NCTN) was formed and within it was established a Diagnostic Imaging and Radiation Therapy Quality Assurance Organization. This organization is Imaging and Radiation Oncology Core, the Imaging and Radiation Oncology Core Group, consisting of 6 quality assurance centers that provide imaging and radiation therapy quality assurance for the NCTN. Sophisticated imaging is used for cancer diagnosis, treatment, and management as well as for image-driven technologies to plan and execute radiation treatment. Integration of imaging and radiation oncology data acquisition, review, management, and archive strategies are essential for trial compliance and future research. Lessons learned from previous trials are and provide evidence to support diagnostic imaging and radiation therapy data acquisition in NCTN trials.
AB - Cancer treatment evolves through oncology clinical trials. Cancer trials are multimodal and complex. Assuring high-quality data are available to answer not only study objectives but also questions not anticipated at study initiation is the role of quality assurance. The National Cancer Institute reorganized its cancer clinical trials program in 2014. The National Clinical Trials Network (NCTN) was formed and within it was established a Diagnostic Imaging and Radiation Therapy Quality Assurance Organization. This organization is Imaging and Radiation Oncology Core, the Imaging and Radiation Oncology Core Group, consisting of 6 quality assurance centers that provide imaging and radiation therapy quality assurance for the NCTN. Sophisticated imaging is used for cancer diagnosis, treatment, and management as well as for image-driven technologies to plan and execute radiation treatment. Integration of imaging and radiation oncology data acquisition, review, management, and archive strategies are essential for trial compliance and future research. Lessons learned from previous trials are and provide evidence to support diagnostic imaging and radiation therapy data acquisition in NCTN trials.
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U2 - 10.1016/j.ijrobp.2015.10.028
DO - 10.1016/j.ijrobp.2015.10.028
M3 - Review article
C2 - 26853346
AN - SCOPUS:84953380967
SN - 0360-3016
VL - 94
SP - 404
EP - 411
JO - International Journal of Radiation Oncology Biology Physics
JF - International Journal of Radiation Oncology Biology Physics
IS - 2
ER -