Image registration of SPECT and CT images using an external fiduciary band and three-dimensional surface fitting in metastatic thyroid cancer

A. M. Scott, H. Macapinlac, J. Zhang, F. Daghighian, N. Montemayor, H. Kalaigian, G. Sgouros, M. C. Graham, K. Kolbert, S. D.J. Yeh, E. Lai, S. J. Goldsmith, S. M. Larson

Research output: Contribution to journalArticlepeer-review

Abstract

Image registration of 131I SPECT with CT scans was performed in a patient with metastatic thyroid carcinoma using an external fiduciary band and a three-dimensional surface-fitting algorithm. Areas of metastatic disease taking up 131I were accurately localized to the liver, lungs and vertebral bodies; providing information that could not be obtained by planar or SPECT images alone. Based on these findings, further invasive diagnostic procedures were not performed, therefore considerably altering management in this patient. This approach to image registration has immediate clinical utility in the registration and interpretation of SPECT studies with corresponding CT or MRI scans.

Original languageEnglish (US)
Pages (from-to)100-103
Number of pages4
JournalJournal of Nuclear Medicine
Volume36
Issue number1
StatePublished - Jan 1 1995
Externally publishedYes

Keywords

  • external fiduciary band
  • image registration
  • three-dimensional surface fitting

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

Fingerprint Dive into the research topics of 'Image registration of SPECT and CT images using an external fiduciary band and three-dimensional surface fitting in metastatic thyroid cancer'. Together they form a unique fingerprint.

Cite this