Image-guided core breast biopsy of ductal carcinoma in situ presenting as a non-calcified abnormality

Pamela J. DiPiro, Jack E. Meyer, Christine M. Denison, Thomas H. Frenna, Susan Harvey, Darrell N. Smith

Research output: Contribution to journalArticle

Abstract

Objective: Ductal carcinoma in situ (DCIS) typically presents as calcifications which are detected mammographically. Our aim was to evaluate the less common presentations of ductal carcinoma in situ diagnosed by image- guided core biopsy and correlate with histopathologic diagnoses. Methods and Material: Imaging and histopathologic findings were retrospectively reviewed in 11 patients with ductal carcinoma in situ diagnosed at core biopsy that presented as noncalcified radiographic abnormalities. Results: Mammography showed non-calcified, circumscribed nodules, ill-defined nodules and architectural distortion. In two patients, no mammographic abnormality was detected. Sonography showed circumscribed, round or oval, solid masses; irregular, heterogeneous masses; and a tubular structure. Histopathologic diagnoses included multiple architectural subtypes and ranged from low to high nuclear grade. Conclusion: Although image-guided core biopsy diagnosis of ductal carcinoma is typically made when sampling calcifications, DCIS can be diagnosed following biopsy of non-calcified masses or distortion. There is no correlation between histopathologic subtype and radiologic appearance.

Original languageEnglish (US)
Pages (from-to)231-236
Number of pages6
JournalEuropean Journal of Radiology
Volume30
Issue number3
DOIs
StatePublished - Jun 1999
Externally publishedYes

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Carcinoma, Intraductal, Noninfiltrating
Breast
Image-Guided Biopsy
Biopsy
Ductal Carcinoma
Mammography
Ultrasonography

Keywords

  • Core breast biopsy
  • Ductal carcinoma in situ (DCIS)

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

Cite this

Image-guided core breast biopsy of ductal carcinoma in situ presenting as a non-calcified abnormality. / DiPiro, Pamela J.; Meyer, Jack E.; Denison, Christine M.; Frenna, Thomas H.; Harvey, Susan; Smith, Darrell N.

In: European Journal of Radiology, Vol. 30, No. 3, 06.1999, p. 231-236.

Research output: Contribution to journalArticle

DiPiro, Pamela J. ; Meyer, Jack E. ; Denison, Christine M. ; Frenna, Thomas H. ; Harvey, Susan ; Smith, Darrell N. / Image-guided core breast biopsy of ductal carcinoma in situ presenting as a non-calcified abnormality. In: European Journal of Radiology. 1999 ; Vol. 30, No. 3. pp. 231-236.
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AU - Harvey, Susan

AU - Smith, Darrell N.

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