Image-based estimation of ventricular fiber orientations for patient-specific simulations.

Fijoy Vadakkumpadan, Hermenegild Arevalo, Can Ceritoglu, Michael Miller, Natalia Trayanova

Research output: Contribution to journalArticle

Abstract

Patient-specific simulation of heart (dys)function aimed at personalizing cardiac therapy are hampered by the absence of in vivo imaging technology for clinically acquiring myocardial fiber orientations. In this research, we develop a methodology to predict ventricular fiber orientations of a patient heart, given the geometry of the heart and an atlas. We test the methodology by comparing the estimated fiber orientations with measured ones, and by quantifying the effect of the estimation error on outcomes of electrophysiological simulations, in normal and failing canine hearts. The new insights obtained from the project will pave the way for the development of patient-specific models of the heart that can aid physicians in personalized diagnosis and decisions regarding electrophysiological interventions.

Original languageEnglish (US)
Pages (from-to)1672-1675
Number of pages4
JournalConference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference
Volume2011
StatePublished - 2011
Externally publishedYes

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Patient Simulation
Fiber reinforced materials
Atlases
Error analysis
Canidae
Technology
Physicians
Imaging techniques
Geometry
Research

ASJC Scopus subject areas

  • Computer Vision and Pattern Recognition
  • Signal Processing
  • Biomedical Engineering
  • Health Informatics

Cite this

Image-based estimation of ventricular fiber orientations for patient-specific simulations. / Vadakkumpadan, Fijoy; Arevalo, Hermenegild; Ceritoglu, Can; Miller, Michael; Trayanova, Natalia.

In: Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference, Vol. 2011, 2011, p. 1672-1675.

Research output: Contribution to journalArticle

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