ILOOP - A web application for two-channel microarray interwoven loop design

Mehdi Pirooznia, Ping Gong, Jack Y. Yang, Mary Qu Yang, Edward J. Perkins, Youping Deng

Research output: Contribution to journalArticlepeer-review

6 Scopus citations

Abstract

Microarray technology is widely applied to address complex scientific questions. However, there remain fundamental issues on how to design experiments to ensure that the resulting data enables robust statistical analysis. Interwoven loop design has several advantages over other designs. However it suffers in the complexity of design. We have implemented an online web application which allows users to find optimal loop designs for two-color microarray experiments. Given a number of conditions (such as treatments or time points) and replicates, the application will find the best possible design of the experiment and output experimental parameters.

Original languageEnglish (US)
Article numberS11
JournalBMC Genomics
Volume9
Issue numberSUPPL. 2
DOIs
StatePublished - Sep 16 2008
Externally publishedYes

ASJC Scopus subject areas

  • Biotechnology
  • Genetics

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