Abstract
That conditioning on a common effect of exposure and outcome may cause selection, or collider-stratification, bias is not intuitive. We provide two hypothetical examples to convey concepts underlying bias due to conditioning on a collider. In the first example, fever is a common effect of influenza and consumption of a tainted egg-salad sandwich. In the second example, case-status is a common effect of a genotype and an environmental factor. In both examples, conditioning on the common effect imparts an association between two otherwise independent variables; we call this selection bias.
| Original language | English (US) |
|---|---|
| Article number | dyp334 |
| Pages (from-to) | 417-420 |
| Number of pages | 4 |
| Journal | International Journal of Epidemiology |
| Volume | 39 |
| Issue number | 2 |
| DOIs | |
| State | Published - Apr 2010 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Epidemiology
Cite this
Illustrating bias due to conditioning on a collider. / Cole, Stephen R.; Platt, Robert W.; Schisterman, Enrique F.; Chu, Haitao; Westreich, Daniel; Richardson, David; Poole, Charles.
In: International Journal of Epidemiology, Vol. 39, No. 2, dyp334, 04.2010, p. 417-420.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Illustrating bias due to conditioning on a collider
AU - Cole, Stephen R.
AU - Platt, Robert W.
AU - Schisterman, Enrique F.
AU - Chu, Haitao
AU - Westreich, Daniel
AU - Richardson, David
AU - Poole, Charles
PY - 2010/4
Y1 - 2010/4
N2 - That conditioning on a common effect of exposure and outcome may cause selection, or collider-stratification, bias is not intuitive. We provide two hypothetical examples to convey concepts underlying bias due to conditioning on a collider. In the first example, fever is a common effect of influenza and consumption of a tainted egg-salad sandwich. In the second example, case-status is a common effect of a genotype and an environmental factor. In both examples, conditioning on the common effect imparts an association between two otherwise independent variables; we call this selection bias.
AB - That conditioning on a common effect of exposure and outcome may cause selection, or collider-stratification, bias is not intuitive. We provide two hypothetical examples to convey concepts underlying bias due to conditioning on a collider. In the first example, fever is a common effect of influenza and consumption of a tainted egg-salad sandwich. In the second example, case-status is a common effect of a genotype and an environmental factor. In both examples, conditioning on the common effect imparts an association between two otherwise independent variables; we call this selection bias.
UR - http://www.scopus.com/inward/record.url?scp=77952717253&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=77952717253&partnerID=8YFLogxK
U2 - 10.1093/ije/dyp334
DO - 10.1093/ije/dyp334
M3 - Article
VL - 39
SP - 417
EP - 420
JO - International Journal of Epidemiology
JF - International Journal of Epidemiology
SN - 0300-5771
IS - 2
M1 - dyp334
ER -