Illustrating bias due to conditioning on a collider

Stephen R. Cole, Robert W. Platt, Enrique F. Schisterman, Haitao Chu, Daniel Westreich, David Richardson, Charles Poole

Research output: Contribution to journalArticle

Abstract

That conditioning on a common effect of exposure and outcome may cause selection, or collider-stratification, bias is not intuitive. We provide two hypothetical examples to convey concepts underlying bias due to conditioning on a collider. In the first example, fever is a common effect of influenza and consumption of a tainted egg-salad sandwich. In the second example, case-status is a common effect of a genotype and an environmental factor. In both examples, conditioning on the common effect imparts an association between two otherwise independent variables; we call this selection bias.

Original languageEnglish (US)
Article numberdyp334
Pages (from-to)417-420
Number of pages4
JournalInternational Journal of Epidemiology
Volume39
Issue number2
DOIs
StatePublished - Apr 2010
Externally publishedYes

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Selection Bias
Human Influenza
Ovum
Fever
Genotype

ASJC Scopus subject areas

  • Epidemiology

Cite this

Cole, S. R., Platt, R. W., Schisterman, E. F., Chu, H., Westreich, D., Richardson, D., & Poole, C. (2010). Illustrating bias due to conditioning on a collider. International Journal of Epidemiology, 39(2), 417-420. [dyp334]. https://doi.org/10.1093/ije/dyp334

Illustrating bias due to conditioning on a collider. / Cole, Stephen R.; Platt, Robert W.; Schisterman, Enrique F.; Chu, Haitao; Westreich, Daniel; Richardson, David; Poole, Charles.

In: International Journal of Epidemiology, Vol. 39, No. 2, dyp334, 04.2010, p. 417-420.

Research output: Contribution to journalArticle

Cole, SR, Platt, RW, Schisterman, EF, Chu, H, Westreich, D, Richardson, D & Poole, C 2010, 'Illustrating bias due to conditioning on a collider', International Journal of Epidemiology, vol. 39, no. 2, dyp334, pp. 417-420. https://doi.org/10.1093/ije/dyp334
Cole SR, Platt RW, Schisterman EF, Chu H, Westreich D, Richardson D et al. Illustrating bias due to conditioning on a collider. International Journal of Epidemiology. 2010 Apr;39(2):417-420. dyp334. https://doi.org/10.1093/ije/dyp334
Cole, Stephen R. ; Platt, Robert W. ; Schisterman, Enrique F. ; Chu, Haitao ; Westreich, Daniel ; Richardson, David ; Poole, Charles. / Illustrating bias due to conditioning on a collider. In: International Journal of Epidemiology. 2010 ; Vol. 39, No. 2. pp. 417-420.
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