Illicit use of clonidine in opiate-abusing pregnant women

Frank Anderson, Pat Paluzzi, Jana Lee, George R. Huggins, Dace Svikis

Research output: Contribution to journalArticle

Abstract

Objective: To examine prevalence rates and psychosocial correlates of clonidine use in a sample of opiate-dependent pregnant women. Methods: Clonidine use was assessed in 90 treatment-seeking, pregnant, opiate-abusing women using both self-report and urinalysis toxicology. Clonidine-positive and -negative subjects were compared for selected demographic, substance use, and psychosocial measures. Results: One-third of the sample was clonidine- positive. Urinalysis identified 26 clonidine-positive subjects, whereas self- report detected only six cases. Logistic regression identified four predictors of clonidine use at treatment admission: recent clinical anxiety, greater severity of family or social problems, recent cocaine use, and recent drug treatment. Conclusion: Clonidine use is prevalent in treatment-seeking opiate abusers, particularly those with concurrent cocaine use. The abuse potential of the drug warrants further study in this high-risk population.

Original languageEnglish (US)
Pages (from-to)790-794
Number of pages5
JournalObstetrics and Gynecology
Volume90
Issue number5
DOIs
StatePublished - Nov 1997

Fingerprint

Opiate Alkaloids
Clonidine
Pregnant Women
Urinalysis
Cocaine
Self Report
Social Problems
Therapeutics
Toxicology
Substance-Related Disorders
Anxiety
Logistic Models
Demography

ASJC Scopus subject areas

  • Obstetrics and Gynecology

Cite this

Illicit use of clonidine in opiate-abusing pregnant women. / Anderson, Frank; Paluzzi, Pat; Lee, Jana; Huggins, George R.; Svikis, Dace.

In: Obstetrics and Gynecology, Vol. 90, No. 5, 11.1997, p. 790-794.

Research output: Contribution to journalArticle

Anderson, Frank ; Paluzzi, Pat ; Lee, Jana ; Huggins, George R. ; Svikis, Dace. / Illicit use of clonidine in opiate-abusing pregnant women. In: Obstetrics and Gynecology. 1997 ; Vol. 90, No. 5. pp. 790-794.
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