IKDCs or B220 + NK cells are pre-mNK cells

Laurence Zitvogel, Franck Housseau

Research output: Contribution to journalComment/debatepeer-review


The cell lineage origin of interferon-producing killer dendritic cells (IKDCs) has been challenged since 2006 when the unique capacity of these cells to accumulate in tumors and mediate remarkable antitumor effects was first described. 1-4 In this issue of Blood, Guimont-Desrochers et al redefine B220 + NK cells as a novel intermediate in NK-cell differentiation preceding the acquisition of CD27.

Original languageEnglish (US)
Pages (from-to)4345-4346
Number of pages2
Issue number19
StatePublished - May 10 2012

ASJC Scopus subject areas

  • Biochemistry
  • Immunology
  • Hematology
  • Cell Biology

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