IgE and FcεRI regulation

Research output: Contribution to journalReview article

Abstract

The high-affinity immunoglobulin (Ig)E receptor, FcεRI, regulates the action of mast cells and basophils and therefore, regulates the expression of atopic disease. There have been several recent observations that demonstrate new beaviors for this receptor. The control of FcεRI expression, control of cell function by FcεRI, and expression of FcεRI on other cell types are important new areas of understanding currently being explored.

Original languageEnglish (US)
Pages (from-to)49-60
Number of pages12
JournalClinical Reviews in Allergy and Immunology
Volume29
Issue number1
DOIs
StatePublished - Aug 2005

Keywords

  • FcεRI regulation
  • Ige
  • Mast cells, basophils, dendritic cells, signal transduction, atopy

ASJC Scopus subject areas

  • Immunology and Allergy

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