TY - JOUR
T1 - Idiopathic scleredema
AU - Ng, Elise
AU - Rosenstein, Rachel
AU - Terushkin, Vitaly
AU - Meehan, Shane
AU - Pomeranz, Miriam Keltz
N1 - Publisher Copyright:
© 2016 by the article author(s). All rights reserved.
PY - 2016
Y1 - 2016
N2 - Scleredema, which also is known as scleredema adultorum of Buschke, is an uncommon sclerodermiform condition that is characterized by progressive thickening and hardening of the skin due to excessive dermal mucin and collagen deposition. The clinical course is variable, and progression of disease may lead to functional impairment with limitations in mobility. The etiology and pathogenesis are unknown although several well-known associations include streptococcal infection; diabetes mellitus, particularly with metabolic syndrome; and monoclonal gammopathy. We present a case of scleredema in a 52-year-old man with no identifiable associated condition, who experienced improvemement with UVB phototherapy.
AB - Scleredema, which also is known as scleredema adultorum of Buschke, is an uncommon sclerodermiform condition that is characterized by progressive thickening and hardening of the skin due to excessive dermal mucin and collagen deposition. The clinical course is variable, and progression of disease may lead to functional impairment with limitations in mobility. The etiology and pathogenesis are unknown although several well-known associations include streptococcal infection; diabetes mellitus, particularly with metabolic syndrome; and monoclonal gammopathy. We present a case of scleredema in a 52-year-old man with no identifiable associated condition, who experienced improvemement with UVB phototherapy.
UR - http://www.scopus.com/inward/record.url?scp=85006954218&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85006954218&partnerID=8YFLogxK
M3 - Article
C2 - 28329532
AN - SCOPUS:85006954218
SN - 1087-2108
VL - 22
SP - 5
EP - 7
JO - Dermatology online journal
JF - Dermatology online journal
IS - 12
ER -