Idiopathic chondrolysis condition in two young, wild-caught cynomolgus monkeys (Macaca fascicularis) reared in captivity

S. Rao, M. Bryant, R. Herbert, N. Sullivan, C. Murray, J. Bacher, N. Safdar

Research output: Contribution to journalArticlepeer-review

Abstract

Idiopathic chondrolysis is a human clinical entity typically reported in adolescent individuals. In this brief communication, we report 2 cases of presumptive idiopathic chondrolysis of the femoral head in Cynomolgus macaques and discuss the clinical symptomatology and pathology of the disease. In detail, we describe the histomorphologic changes of idiopathic chondrolysis and compare these findings with those typically observed in the primary differential diagnoses of Legg-Calve-Perthes disease and nonspecific osteoarthritis. Consideration of this entity among differential diagnoses in young Cynomolgus macaques with unilateral osteoarthritis could be important both for laboratory animal veterinarians and pathologists.

Original languageEnglish (US)
Pages (from-to)509-513
Number of pages5
JournalVeterinary pathology
Volume46
Issue number3
DOIs
StatePublished - May 2009

Keywords

  • Cynomolgus monkey
  • Femoral head degenerative joint disease
  • Idiopathic chondrolysis
  • Legg-calve-perthes
  • Macaque
  • Osteoarthritis

ASJC Scopus subject areas

  • veterinary(all)

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