Identification of the human papillomavirus E2 protein in genital tract tissues

C. C.H. Li, R. V. Gilden, S. D. Showalter, K. V. Shah

Research output: Contribution to journalArticle

Abstract

A 27-kilodalton protein representing ~60% of the E2 open reading frame of human papillomavirus type 6 (HPV-6) was synthesized in a bacterial expression system. Affinity-purified polyclonal antibody to this protein detected the probable E2 gene product as a 50-kilodalton protein in most condylomas by Western blot (immunoblot) analysis. The E2-positive condylomas were associated with HPV-6, HPV-11, HPV-16, or unidentified HPVs.

Original languageEnglish (US)
Pages (from-to)606-609
Number of pages4
JournalJournal of virology
Volume62
Issue number2
DOIs
StatePublished - 1988

ASJC Scopus subject areas

  • Microbiology
  • Immunology
  • Insect Science
  • Virology

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