Identification of seizure pathways by spectral analysis of EEG

Yien Che Tsai; David L. Sherman; Lisa Ann Rossell; Marek A. Mirski; Nitish V. Thakor

Identification of seizure pathways by spectral analysis of EEG

Yien Che Tsai, David L. Sherman, Lisa Ann Rossell, Marek A. Mirski, Nitish V. Thakor

School of Medicine

Research output: Contribution to journal › Conference article › peer-review

Abstract

We hypothesize that anterior thalamus, a subcortical center important for seizure expression, exhibits high signal coherence with cortex during a clonic seizure expression. In addition, the partial coherence would not vanish when the effects of an inert center are removed by a partial regression analysis. Generalized seizures are induced in rats (n = 6) using pentylentetrazol (PTZ) and EEG recorded from cortical and subcortical sites. Statistical analysis of coherence and partial coherence indicates that anterior thalamic and cortical EEG are highly coherent during a clonic seizure expression. Coherence analysis can therefore provide details of the pathway for the spread of seizure activities between subcortical and cortical brain.

Original language	English (US)
Pages (from-to)	897-898
Number of pages	2
Journal	Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
Volume	17
Issue number	2
State	Published - Dec 1 1995
Event	Proceedings of the 1995 IEEE Engineering in Medicine and Biology 17th Annual Conference and 21st Canadian Medical and Biological Engineering Conference. Part 2 (of 2) - Montreal, Can Duration: Sep 20 1995 → Sep 23 1995

ASJC Scopus subject areas

Signal Processing
Biomedical Engineering
Computer Vision and Pattern Recognition
Health Informatics

Cite this

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title = "Identification of seizure pathways by spectral analysis of EEG",

abstract = "We hypothesize that anterior thalamus, a subcortical center important for seizure expression, exhibits high signal coherence with cortex during a clonic seizure expression. In addition, the partial coherence would not vanish when the effects of an inert center are removed by a partial regression analysis. Generalized seizures are induced in rats (n = 6) using pentylentetrazol (PTZ) and EEG recorded from cortical and subcortical sites. Statistical analysis of coherence and partial coherence indicates that anterior thalamic and cortical EEG are highly coherent during a clonic seizure expression. Coherence analysis can therefore provide details of the pathway for the spread of seizure activities between subcortical and cortical brain.",

author = "Tsai, {Yien Che} and Sherman, {David L.} and Rossell, {Lisa Ann} and Mirski, {Marek A.} and Thakor, {Nitish V.}",

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note = "Proceedings of the 1995 IEEE Engineering in Medicine and Biology 17th Annual Conference and 21st Canadian Medical and Biological Engineering Conference. Part 2 (of 2) ; Conference date: 20-09-1995 Through 23-09-1995",

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TY - JOUR

T1 - Identification of seizure pathways by spectral analysis of EEG

AU - Tsai, Yien Che

AU - Sherman, David L.

AU - Rossell, Lisa Ann

AU - Mirski, Marek A.

AU - Thakor, Nitish V.

PY - 1995/12/1

Y1 - 1995/12/1

N2 - We hypothesize that anterior thalamus, a subcortical center important for seizure expression, exhibits high signal coherence with cortex during a clonic seizure expression. In addition, the partial coherence would not vanish when the effects of an inert center are removed by a partial regression analysis. Generalized seizures are induced in rats (n = 6) using pentylentetrazol (PTZ) and EEG recorded from cortical and subcortical sites. Statistical analysis of coherence and partial coherence indicates that anterior thalamic and cortical EEG are highly coherent during a clonic seizure expression. Coherence analysis can therefore provide details of the pathway for the spread of seizure activities between subcortical and cortical brain.

AB - We hypothesize that anterior thalamus, a subcortical center important for seizure expression, exhibits high signal coherence with cortex during a clonic seizure expression. In addition, the partial coherence would not vanish when the effects of an inert center are removed by a partial regression analysis. Generalized seizures are induced in rats (n = 6) using pentylentetrazol (PTZ) and EEG recorded from cortical and subcortical sites. Statistical analysis of coherence and partial coherence indicates that anterior thalamic and cortical EEG are highly coherent during a clonic seizure expression. Coherence analysis can therefore provide details of the pathway for the spread of seizure activities between subcortical and cortical brain.

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M3 - Conference article

AN - SCOPUS:0029428972

SN - 0589-1019

VL - 17

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EP - 898

JO - Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings

JF - Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings

IS - 2

T2 - Proceedings of the 1995 IEEE Engineering in Medicine and Biology 17th Annual Conference and 21st Canadian Medical and Biological Engineering Conference. Part 2 (of 2)

Y2 - 20 September 1995 through 23 September 1995

ER -

Identification of seizure pathways by spectral analysis of EEG

Abstract

ASJC Scopus subject areas

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