Identification of myocardial infarction using three-dimensional strain tensor fractional anisotropy

Sahar Soleimanifard, Khaled Z. Abd-Elmoniem, Harsh K. Agarwal, Miguel S. Tomas, Tetsuo Sasano, Evertjan Vonken, Amr Youssef, M. Roselle Abraham, Theodore P. Abraham, Jerry L. Prince

Research output: Chapter in Book/Report/Conference proceedingConference contribution

3 Scopus citations

Abstract

Accurate localization of myocardial viability is important in diagnosis of infarction. Regional strain function provides excessive information for clinical decision making but comparison of strain tensor profiles across differing tissue types is usually difficult due to multi-variate nature of tensors. It is desirable to describe tensors with simplified scalar indices which are more mathematically and statistically intuitive. In this work, anisotropy of tensors in healthy and experimental infarct regions in a large animal model is assessed and compared to directional components of strain tensors which are currently the most popular indices in active use. Myocardial strain tensors are computed using zHARP, a magnetic resonance (MR) tagging technique that provides quantification of cardiac function with direct computation of three-dimensional ensors from two-dimensional short axis MR images. Fractional anisotropy of strain tensors shows high correlation with late gadolinium enhanced images and is capable of discrimination between healthy and infarcted regions.

Original languageEnglish (US)
Title of host publication2010 7th IEEE International Symposium on Biomedical Imaging
Subtitle of host publicationFrom Nano to Macro, ISBI 2010 - Proceedings
Pages468-471
Number of pages4
DOIs
StatePublished - 2010
Event7th IEEE International Symposium on Biomedical Imaging: From Nano to Macro, ISBI 2010 - Rotterdam, Netherlands
Duration: Apr 14 2010Apr 17 2010

Publication series

Name2010 7th IEEE International Symposium on Biomedical Imaging: From Nano to Macro, ISBI 2010 - Proceedings

Other

Other7th IEEE International Symposium on Biomedical Imaging: From Nano to Macro, ISBI 2010
Country/TerritoryNetherlands
CityRotterdam
Period4/14/104/17/10

Keywords

  • Fractional anisotropy
  • HARP
  • Infarction
  • Strain tensor
  • zHARP

ASJC Scopus subject areas

  • Biomedical Engineering
  • Radiology Nuclear Medicine and imaging

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