Identification of a large molecular weight peptide associated with a tetrodotoxin binding protein from the electroplax of Electrophorus electricus

William S. Agnew; Anne C. Moore; Simon R. Levinson; Michael A. Raftery

doi:10.1016/0006-291X(80)90782-2

Identification of a large molecular weight peptide associated with a tetrodotoxin binding protein from the electroplax of Electrophorus electricus

William S. Agnew, Anne C. Moore, Simon R. Levinson, Michael A. Raftery

Research output: Contribution to journal › Article › peer-review

62 Scopus citations

Abstract

We have previously described the purification of a tetrodotoxin binding protein from the electroplax of Electrophorus electricus. The preparation consisted of three peptides of M_r ∼ 46,000, 59,000 and ∼ 300,000 daltons. Further investigation has now shown that the large peptide of M_r ∼ 260,000 daltons is part of the tetrodotoxin binding component of the voltage-sensitive sodium channel.

Original language	English (US)
Pages (from-to)	860-866
Number of pages	7
Journal	Biochemical and Biophysical Research Communications
Volume	92
Issue number	3
DOIs	https://doi.org/10.1016/0006-291X(80)90782-2
State	Published - Feb 12 1980
Externally published	Yes

ASJC Scopus subject areas

Biophysics
Biochemistry
Molecular Biology
Cell Biology

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10.1016/0006-291X(80)90782-2

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Identification of a large molecular weight peptide associated with a tetrodotoxin binding protein from the electroplax of Electrophorus electricus. / Agnew, William S.; Moore, Anne C.; Levinson, Simon R. et al.

In: Biochemical and Biophysical Research Communications, Vol. 92, No. 3, 12.02.1980, p. 860-866.

Research output: Contribution to journal › Article › peer-review

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abstract = "We have previously described the purification of a tetrodotoxin binding protein from the electroplax of Electrophorus electricus. The preparation consisted of three peptides of Mr ∼ 46,000, 59,000 and ∼ 300,000 daltons. Further investigation has now shown that the large peptide of Mr ∼ 260,000 daltons is part of the tetrodotoxin binding component of the voltage-sensitive sodium channel.",

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AU - Raftery, Michael A.

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N2 - We have previously described the purification of a tetrodotoxin binding protein from the electroplax of Electrophorus electricus. The preparation consisted of three peptides of Mr ∼ 46,000, 59,000 and ∼ 300,000 daltons. Further investigation has now shown that the large peptide of Mr ∼ 260,000 daltons is part of the tetrodotoxin binding component of the voltage-sensitive sodium channel.

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Identification of a large molecular weight peptide associated with a tetrodotoxin binding protein from the electroplax of Electrophorus electricus

Abstract

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