Abstract
We have previously described the purification of a tetrodotoxin binding protein from the electroplax of Electrophorus electricus. The preparation consisted of three peptides of Mr ∼ 46,000, 59,000 and ∼ 300,000 daltons. Further investigation has now shown that the large peptide of Mr ∼ 260,000 daltons is part of the tetrodotoxin binding component of the voltage-sensitive sodium channel.
Original language | English (US) |
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Pages (from-to) | 860-866 |
Number of pages | 7 |
Journal | Biochemical and Biophysical Research Communications |
Volume | 92 |
Issue number | 3 |
DOIs | |
State | Published - Feb 12 1980 |
Externally published | Yes |
ASJC Scopus subject areas
- Biophysics
- Biochemistry
- Molecular Biology
- Cell Biology