Identification and measurement of testosterone in the sulfate fraction of plasma of normal subjects and patients with gonadal and adrenal disorders

Jose M. Saez, Simone Saez, Claude J. Migeon

Research output: Contribution to journalArticle

Abstract

Testosterone was identified in the sulfate fraction (TS) prepared from human plasma, and a method was devised for its measurement. The plasma concentration of TS in normal subjects was 108 ± 49 mμg/100 ml in nine males and 18 ± 7.5 in four females. Some of the low values obtained in females might be of doubtful significance. In patients with testicular feminization, adrenal tumors, and masculinizing ovarian disorders, the TS concentration in plasma from spermatic, adrenal and ovarian veins, respectively, suggested that TS is secreted by the testes, adrenal tumor and ovaries of these subjects.

Original languageEnglish (US)
Pages (from-to)1-14
Number of pages14
JournalSteroids
Volume9
Issue number1
StatePublished - Jan 1967

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Gonadal Disorders
Sulfates
Testosterone
Tumors
Glandular and Epithelial Neoplasms
Plasma (human)
Plasmas
Androgen-Insensitivity Syndrome
Spermatozoa
Testis
Ovary
Veins

ASJC Scopus subject areas

  • Molecular Biology
  • Endocrinology
  • Biochemistry

Cite this

Identification and measurement of testosterone in the sulfate fraction of plasma of normal subjects and patients with gonadal and adrenal disorders. / Saez, Jose M.; Saez, Simone; Migeon, Claude J.

In: Steroids, Vol. 9, No. 1, 01.1967, p. 1-14.

Research output: Contribution to journalArticle

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