TY - JOUR
T1 - Identification and measurement of testosterone in the sulfate fraction of plasma of normal subjects and patients with gonadal and adrenal disorders
AU - Saez, Jose M.
AU - Saez, Simone
AU - Migeon, Claude J.
PY - 1967/1
Y1 - 1967/1
N2 - Testosterone was identified in the sulfate fraction (TS) prepared from human plasma, and a method was devised for its measurement. The plasma concentration of TS in normal subjects was 108 ± 49 mμg/100 ml in nine males and 18 ± 7.5 in four females. Some of the low values obtained in females might be of doubtful significance. In patients with testicular feminization, adrenal tumors, and masculinizing ovarian disorders, the TS concentration in plasma from spermatic, adrenal and ovarian veins, respectively, suggested that TS is secreted by the testes, adrenal tumor and ovaries of these subjects.
AB - Testosterone was identified in the sulfate fraction (TS) prepared from human plasma, and a method was devised for its measurement. The plasma concentration of TS in normal subjects was 108 ± 49 mμg/100 ml in nine males and 18 ± 7.5 in four females. Some of the low values obtained in females might be of doubtful significance. In patients with testicular feminization, adrenal tumors, and masculinizing ovarian disorders, the TS concentration in plasma from spermatic, adrenal and ovarian veins, respectively, suggested that TS is secreted by the testes, adrenal tumor and ovaries of these subjects.
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U2 - 10.1016/0039-128X(67)90084-0
DO - 10.1016/0039-128X(67)90084-0
M3 - Article
C2 - 6030918
AN - SCOPUS:0014036144
SN - 0039-128X
VL - 9
SP - 1
EP - 14
JO - Steroids
JF - Steroids
IS - 1
ER -