Identification and comparison of eleven rhesus macaque chemokine receptors

B. J. Margulies, D. A. Hauer, J. E. Clements

Research output: Contribution to journalArticle

Abstract

Both simian and human immunodeficiency viruses (SIV and HIV) utilize chemokine receptors, with or without CD4, as portals for entry into susceptible cells. In this report, we present the cloning and comparison of 11 rhesus macaque chemokine receptors and receptor-like proteins (CCR1, CCR2b, CCR3, CCR5, CCR8, CXCR4, STRL33, GPR1, GPR15, APJ, and CRAM-A/B), the human counterparts of which have been previously shown to be utilized by SIV for entry.

Original languageEnglish (US)
Pages (from-to)981-986
Number of pages6
JournalAIDS research and human retroviruses
Volume17
Issue number10
DOIs
StatePublished - Oct 1 2001

ASJC Scopus subject areas

  • Immunology
  • Virology
  • Infectious Diseases

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