TY - JOUR
T1 - Ideal cardiovascular health and resting heart rate in the Multi-Ethnic Study of Atherosclerosis
AU - Osibogun, Olatokunbo
AU - Ogunmoroti, Oluseye
AU - Spatz, Erica S.
AU - Fashanu, Oluwaseun E.
AU - Michos, Erin D.
N1 - Funding Information:
The Multi-Ethnic Study of Atherosclerosis is supported by contracts N01-HC-95159 , N01-HC-95160 , N01-HC-95161 , N01-HC-95162 , N01-HC-95163 , N01-HC-95164 , N01-HC-95165 , N01-HC-95166 , N01-HC-95167 , N01-HC-95168 , N01-HC-95169 and HHSN268201500003I from the National Heart, Lung, and Blood Institute (NHLBI) and by grants UL1-RR-024156 and UL1-RR-025005 from the National Center for Research Resources (NCRR). Dr. Michos is supported by the Blumenthal Scholars Fund for Preventive Cardiology Research . All funding sources have no role in the analysis and interpretation and in the writing of the manuscript.
PY - 2020/1
Y1 - 2020/1
N2 - Elevated resting heart rate (RHR) is associated with an increased cardiovascular disease (CVD) risk, but little is known about its association with cardiovascular health (CVH), assessed by the Life's Simple 7 (LS7) metrics. We explored whether ideal CVH was associated with RHR in a cohort free from clinical CVD. We conducted a cross-sectional analysis of baseline data (2000−2002) of 6457 Multi-Ethnic Study of Atherosclerosis participants in 2018. Each LS7 metric (smoking, physical activity, diet, body mass index, blood pressure, cholesterol and glucose) was scored 0–2. Total score ranged from 0 to 14. Scores of 0–8 indicate inadequate, 9–10 average, and 11–14 optimal CVH. RHR was categorized as <60, 60–69, 70–79 and ≥80 bpm. We used multinomial logistic regression to determine associations between CVH score and RHR, adjusting for age, sex, race/ethnicity, education, income, health insurance, and atrioventricular nodal blockers. Mean age of participants (standard deviation) was 62 (10) years; 53% were women; 47% had inadequate CVH, 33% average, and 20% optimal. Favorable CVH was associated with lower odds of having higher RHR. Compared to RHR <60 bpm, participants with optimal CVH had adjusted odds ratio (95% CI) of 0.55 (0.46–0.64) for RHR of 60-69 bpm, 0.34 (0.28–0.43) for 70–79 bpm, and 0.14 (0.09–0.22) for ≥80 bpm. A similar pattern was observed in the stratified analysis by sex, race/ethnicity and age. Favorable CVH was less likely to be associated with elevated RHR irrespective of sex, race/ethnicity and age. More research is needed to explore the usefulness of promoting ideal CVH to reduce elevated RHR, a known risk factor for CVD.
AB - Elevated resting heart rate (RHR) is associated with an increased cardiovascular disease (CVD) risk, but little is known about its association with cardiovascular health (CVH), assessed by the Life's Simple 7 (LS7) metrics. We explored whether ideal CVH was associated with RHR in a cohort free from clinical CVD. We conducted a cross-sectional analysis of baseline data (2000−2002) of 6457 Multi-Ethnic Study of Atherosclerosis participants in 2018. Each LS7 metric (smoking, physical activity, diet, body mass index, blood pressure, cholesterol and glucose) was scored 0–2. Total score ranged from 0 to 14. Scores of 0–8 indicate inadequate, 9–10 average, and 11–14 optimal CVH. RHR was categorized as <60, 60–69, 70–79 and ≥80 bpm. We used multinomial logistic regression to determine associations between CVH score and RHR, adjusting for age, sex, race/ethnicity, education, income, health insurance, and atrioventricular nodal blockers. Mean age of participants (standard deviation) was 62 (10) years; 53% were women; 47% had inadequate CVH, 33% average, and 20% optimal. Favorable CVH was associated with lower odds of having higher RHR. Compared to RHR <60 bpm, participants with optimal CVH had adjusted odds ratio (95% CI) of 0.55 (0.46–0.64) for RHR of 60-69 bpm, 0.34 (0.28–0.43) for 70–79 bpm, and 0.14 (0.09–0.22) for ≥80 bpm. A similar pattern was observed in the stratified analysis by sex, race/ethnicity and age. Favorable CVH was less likely to be associated with elevated RHR irrespective of sex, race/ethnicity and age. More research is needed to explore the usefulness of promoting ideal CVH to reduce elevated RHR, a known risk factor for CVD.
KW - Ideal cardiovascular health metrics
KW - Life's simple 7
KW - Prevention
KW - Resting heart rate
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U2 - 10.1016/j.ypmed.2019.105890
DO - 10.1016/j.ypmed.2019.105890
M3 - Article
C2 - 31715219
AN - SCOPUS:85075041188
VL - 130
JO - Preventive Medicine
JF - Preventive Medicine
SN - 0091-7435
M1 - 105890
ER -