I. Indocyanine Green Should Be Used to Facilitate Removal of the Internal Limiting Membrane in Macular Hole Surgery. Should Indocyanine Green Be Used to Faciliate Removal of the Internal Limiting Membrane in Macular Hole Surgery?

John T. Thompson

Research output: Contribution to journalArticle


Indocyanine green (ICG) is one of several vital dyes that are used in vitreoretinal surgery to aid visualization of diaphanous collagenous tissues in what has been called chromovitrectomy. As shown herein, much has been written about the use and rather narrow safety profile of ICG. The discussion surrounding its applications would have ended long ago were it not for the occasional patient who keeps returning to the office with permanent central scotomas after ICG-assisted macular hole surgery. The purpose of this Viewpoint is to reemphasize potential methods of proper use and clarify safety issues of this particular vital dye that enhances surgical technique but not necessarily visual outcome.

Original languageEnglish (US)
Pages (from-to)135-138
Number of pages4
JournalSurvey of Ophthalmology
Issue number1
Publication statusPublished - Jan 2009
Externally publishedYes



  • chromovitrectomy
  • indocyanine green
  • internal limiting membrane
  • macular hole surery
  • toxicity

ASJC Scopus subject areas

  • Ophthalmology

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