Hypoxic-ischemic brain injury in neonatal piglets with different histological outcomes: An amplitude-integrated EEG study.

Dandan Zhang; Manan Hathi; Zeng Jin Yang; Haiyan Ding; Raymond Koehler; Nitish Thakor

Hypoxic-ischemic brain injury in neonatal piglets with different histological outcomes: An amplitude-integrated EEG study.

Dandan Zhang, Manan Hathi, Zeng Jin Yang, Haiyan Ding, Raymond Koehler, Nitish Thakor

Research output: Contribution to journal › Article › peer-review

Abstract

To test the reliability of amplitude-integrated electroencephalogram (aEEG) in cerebral hypoxic ischemia (HI), 12 neonatal piglets subjected to different levels of HI are divided into three groups based on the histological outcomes obtained 4 days after experiment. Results show that concomitant with the increased severity of brain injury, the upper and lower margins of aEEG decrease significantly (p <0.05) during early recovery period after HI (about 2 hours post-resuscitation). We conclude that aEEG method reliably reflects hypoxic-ischemic cerebral injury and constitutes a valuable monitoring tool in neonatal intensive care unit (NICU).

Original language	English (US)
Pages (from-to)	1127-1130
Number of pages	4
Journal	Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference
State	Published - 2009
Externally published	Yes

ASJC Scopus subject areas

Computer Vision and Pattern Recognition
Signal Processing
Biomedical Engineering
Health Informatics

Cite this

Zhang, D., Hathi, M., Yang, Z. J., Ding, H., Koehler, R., & Thakor, N. (2009). Hypoxic-ischemic brain injury in neonatal piglets with different histological outcomes: An amplitude-integrated EEG study. Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference, 1127-1130.

Hypoxic-ischemic brain injury in neonatal piglets with different histological outcomes: An amplitude-integrated EEG study. / Zhang, Dandan; Hathi, Manan; Yang, Zeng Jin et al.
In: Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference, 2009, p. 1127-1130.

Research output: Contribution to journal › Article › peer-review

Zhang, D, Hathi, M, Yang, ZJ, Ding, H, Koehler, R & Thakor, N 2009, 'Hypoxic-ischemic brain injury in neonatal piglets with different histological outcomes: An amplitude-integrated EEG study.', Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference, pp. 1127-1130.

Zhang D, Hathi M, Yang ZJ, Ding H, Koehler R , Thakor N. Hypoxic-ischemic brain injury in neonatal piglets with different histological outcomes: An amplitude-integrated EEG study. Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference. 2009;1127-1130.

Zhang, Dandan ; Hathi, Manan ; Yang, Zeng Jin et al. / Hypoxic-ischemic brain injury in neonatal piglets with different histological outcomes : An amplitude-integrated EEG study. In: Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference. 2009 ; pp. 1127-1130.

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Hypoxic-ischemic brain injury in neonatal piglets with different histological outcomes: An amplitude-integrated EEG study.

Abstract

ASJC Scopus subject areas

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