Hypoxia-inducible factor 1: Master regulator of O2 homeostasis

Research output: Contribution to journalArticlepeer-review

Abstract

Hypoxia-inducible factor 1 (HIF-1) is a transcription factor that mediates essential homeostatic responses to reduced O2 availability in mammals. Recent studies have provided insights into the O2-dependent regulation of HIF-1 expression, target genes regulated by HIF-1, and the effects of HIF-1 deficiency on cellular physiology and embryonic development.

Original languageEnglish (US)
Pages (from-to)588-594
Number of pages7
JournalCurrent Opinion in Genetics and Development
Volume8
Issue number5
DOIs
StatePublished - Oct 1998

ASJC Scopus subject areas

  • Genetics
  • Developmental Biology

Fingerprint Dive into the research topics of 'Hypoxia-inducible factor 1: Master regulator of O<sub>2</sub> homeostasis'. Together they form a unique fingerprint.

Cite this