Hypoimmunoglobulin G, Hyperimmunoglobulin M, Intestinal Nodular Hyperplasia, and Thrombocytopenia: An unusual association

Gary W. Goldstein, William J. Krivit, Richard Hong

Research output: Contribution to journalArticle

Abstract

A case of hypo-IgG, hyper-IgM, nodular intestinal lymphoid hyperplasia, hepatosplenomegaly, and thrombocytopenia is described. The association of defects is consistent with the idea that the development of the lymphoid and haematological systems are intimately related, and probably dependent upon a common cell of origin, and suggests a relation of the intestinal lymphoid tissue to immunoglobulin production. No unusual susceptibility to pyogenic infection has as yet been noted in this patient.

Original languageEnglish (US)
Pages (from-to)621-624
Number of pages4
JournalArchives of disease in childhood
Volume44
Issue number237
DOIs
StatePublished - 1969

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

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