A case of hypo-IgG, hyper-IgM, nodular intestinal lymphoid hyperplasia, hepatosplenomegaly, and thrombocytopenia is described. The association of defects is consistent with the idea that the development of the lymphoid and haematological systems are intimately related, and probably dependent upon a common cell of origin, and suggests a relation of the intestinal lymphoid tissue to immunoglobulin production. No unusual susceptibility to pyogenic infection has as yet been noted in this patient.
ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health