TY - JOUR
T1 - Hypocomplementemic urticarial vasculitis
T2 - Report of a 12-year-old girl with systemic lupus erythematosus
AU - DeAmicis, Tracy
AU - Mofid, Mona Z.
AU - Cohen, Bernard
AU - Nousari, Hossein C.
N1 - Funding Information:
This supplement is made possible through an unrestricted educational grant from Stiefel Laboratories to the American Academy of Dermatology.
Copyright:
Copyright 2018 Elsevier B.V., All rights reserved.
PY - 2002/11/1
Y1 - 2002/11/1
N2 - Urticarial vasculitis, a form of leukocytoclastic vasculitis involving the postcapillaty venules, is classified as a type III hypersensitivity reaction and has been associated with connective tissue disease. The lesions resemble urticaria and typically persist for more than 24 hours. Urticarial vasculitis usually affects young women, and the diagnosis is confirmed at histologic examination. Patients with urticarial vasculitis can be divided into 2 types - those with normal complement levels and those with hypocomplementemic urticarial vasculitis (HUV). Patients with normocomplementemic urticarial vasculitis have a milder course than do patients with HUV, a condition that has a strong association with systemic lupus erythematosus. Angioedema, ocular inflammation, obstructive lung disease, and glomerulonephritis are commonly associated with HUV. We describe the case of a girl with systemic lupus erythematosus and HUV who also had pancreatitis, hypothyroidism, and elevated levels of antiphospholipid antibodies.
AB - Urticarial vasculitis, a form of leukocytoclastic vasculitis involving the postcapillaty venules, is classified as a type III hypersensitivity reaction and has been associated with connective tissue disease. The lesions resemble urticaria and typically persist for more than 24 hours. Urticarial vasculitis usually affects young women, and the diagnosis is confirmed at histologic examination. Patients with urticarial vasculitis can be divided into 2 types - those with normal complement levels and those with hypocomplementemic urticarial vasculitis (HUV). Patients with normocomplementemic urticarial vasculitis have a milder course than do patients with HUV, a condition that has a strong association with systemic lupus erythematosus. Angioedema, ocular inflammation, obstructive lung disease, and glomerulonephritis are commonly associated with HUV. We describe the case of a girl with systemic lupus erythematosus and HUV who also had pancreatitis, hypothyroidism, and elevated levels of antiphospholipid antibodies.
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U2 - 10.1067/mjd.2002.108586
DO - 10.1067/mjd.2002.108586
M3 - Article
C2 - 12399749
AN - SCOPUS:0036828356
SN - 0190-9622
VL - 47
SP - S273-S274
JO - Journal of the American Academy of Dermatology
JF - Journal of the American Academy of Dermatology
IS - 5 SUPPL.
ER -