TY - JOUR
T1 - Hypertrophy of alveolar wall cells secondary to an air pollutant
AU - Sherwin, Russell P.
AU - Sherwin, Russell P.
AU - Margolick, Joseph B.
AU - Azen, Stanley P.
N1 - Funding Information:
This investigation was supported by grants NCAPC 00774 and AP 00604, R 800881, NIHGM 16197-05, and the Hastings Foundation. Gus Faulhaber of the Leitz Co assisted in the operation of the Classimat image analyzer.
Copyright:
Copyright 2016 Elsevier B.V., All rights reserved.
PY - 1973/6
Y1 - 1973/6
N2 - When guinea pigs were exposed to 2 ppm nitrogen dioxide continously for 7, 14, and 21 days, a significant increase was found in the average area per alveolar wall cell (P < .025). The duration of the experiment was also significant (P <.05). The method as used, based on an image analyzer quantitation of 9,824 lactate dehydrogenase- positive alveolar wall cells, can contribute to the basic understanding of the type 2 pneumocyte and potentially to the establishment of air quality standards.
AB - When guinea pigs were exposed to 2 ppm nitrogen dioxide continously for 7, 14, and 21 days, a significant increase was found in the average area per alveolar wall cell (P < .025). The duration of the experiment was also significant (P <.05). The method as used, based on an image analyzer quantitation of 9,824 lactate dehydrogenase- positive alveolar wall cells, can contribute to the basic understanding of the type 2 pneumocyte and potentially to the establishment of air quality standards.
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U2 - 10.1080/00039896.1973.10666285
DO - 10.1080/00039896.1973.10666285
M3 - Article
C2 - 4702723
AN - SCOPUS:0015632691
VL - 26
SP - 297
EP - 299
JO - Archives of Environmental and Occupational Health
JF - Archives of Environmental and Occupational Health
SN - 1933-8244
IS - 6
ER -