Hypertrophic cardiomyopathy: A review

Brian A. Houston, Gerin R. Stevens

Research output: Contribution to journalArticle

Abstract

Hypertrophic cardiomyopathy (HCM) is a global disease with cases reported in all continents, affecting people of both genders and of various racial and ethnic origins. Widely accepted as a monogenic disease caused by a mutation in 1 of 13 or more sarcomeric genes, HCM can present catastrophically with sudden cardiac death (SCD) or ventricular arrhythmias or insidiously with symptoms of heart failure. Given the velocity of progress in both the fields of heart failure and HCM, we present a review of the approach to patients with HCM, with particular attention to those with HCM and the clinical syndrome of heart failure.

Original languageEnglish (US)
Pages (from-to)53-65
Number of pages13
JournalClinical Medicine Insights: Cardiology
Volume8
DOIs
StatePublished - Jan 26 2015

Keywords

  • Heart failure
  • Hypertrophic cardiomyopathy
  • LV hypertrophy

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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