Hypertrophic cardiomyopathy: A review

Brian A. Houston; Gerin R. Stevens

doi:10.4137/CMC.S15717

Hypertrophic cardiomyopathy: A review

Brian A. Houston, Gerin R. Stevens

School of Medicine

Research output: Contribution to journal › Review article › peer-review

30 Scopus citations

Abstract

Hypertrophic cardiomyopathy (HCM) is a global disease with cases reported in all continents, affecting people of both genders and of various racial and ethnic origins. Widely accepted as a monogenic disease caused by a mutation in 1 of 13 or more sarcomeric genes, HCM can present catastrophically with sudden cardiac death (SCD) or ventricular arrhythmias or insidiously with symptoms of heart failure. Given the velocity of progress in both the fields of heart failure and HCM, we present a review of the approach to patients with HCM, with particular attention to those with HCM and the clinical syndrome of heart failure.

Original language	English (US)
Pages (from-to)	53-65
Number of pages	13
Journal	Clinical Medicine Insights: Cardiology
Volume	8
DOIs	https://doi.org/10.4137/CMC.S15717
State	Published - Jan 26 2015

Keywords

Heart failure
Hypertrophic cardiomyopathy
LV hypertrophy

ASJC Scopus subject areas

Cardiology and Cardiovascular Medicine

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10.4137/CMC.S15717

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title = "Hypertrophic cardiomyopathy: A review",

abstract = "Hypertrophic cardiomyopathy (HCM) is a global disease with cases reported in all continents, affecting people of both genders and of various racial and ethnic origins. Widely accepted as a monogenic disease caused by a mutation in 1 of 13 or more sarcomeric genes, HCM can present catastrophically with sudden cardiac death (SCD) or ventricular arrhythmias or insidiously with symptoms of heart failure. Given the velocity of progress in both the fields of heart failure and HCM, we present a review of the approach to patients with HCM, with particular attention to those with HCM and the clinical syndrome of heart failure.",

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AU - Stevens, Gerin R.

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PY - 2015/1/26

Y1 - 2015/1/26

N2 - Hypertrophic cardiomyopathy (HCM) is a global disease with cases reported in all continents, affecting people of both genders and of various racial and ethnic origins. Widely accepted as a monogenic disease caused by a mutation in 1 of 13 or more sarcomeric genes, HCM can present catastrophically with sudden cardiac death (SCD) or ventricular arrhythmias or insidiously with symptoms of heart failure. Given the velocity of progress in both the fields of heart failure and HCM, we present a review of the approach to patients with HCM, with particular attention to those with HCM and the clinical syndrome of heart failure.

AB - Hypertrophic cardiomyopathy (HCM) is a global disease with cases reported in all continents, affecting people of both genders and of various racial and ethnic origins. Widely accepted as a monogenic disease caused by a mutation in 1 of 13 or more sarcomeric genes, HCM can present catastrophically with sudden cardiac death (SCD) or ventricular arrhythmias or insidiously with symptoms of heart failure. Given the velocity of progress in both the fields of heart failure and HCM, we present a review of the approach to patients with HCM, with particular attention to those with HCM and the clinical syndrome of heart failure.

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KW - Hypertrophic cardiomyopathy

KW - LV hypertrophy

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Hypertrophic cardiomyopathy: A review

Abstract

Keywords

ASJC Scopus subject areas

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