TY - JOUR
T1 - Hypertension Awareness, Treatment, and Control in Adults With CKD
T2 - Results From the Chronic Renal Insufficiency Cohort (CRIC) Study
AU - Muntner, Paul
AU - Anderson, Amanda
AU - Charleston, Jeanne
AU - Chen, Zhen
AU - Ford, Virginia
AU - Makos, Gail
AU - O'Connor, Andrew
AU - Perumal, Kalyani
AU - Rahman, Mahboob
AU - Steigerwalt, Susan
AU - Teal, Valerie
AU - Townsend, Raymond
AU - Weir, Matthew
AU - Wright, Jackson T.
N1 - Funding Information:
Support: Dr Muntner received support through a career development grant ( K01 DK064860 ) from the National Institute of Diabetes, Digestive and Kidney Diseases (NIDDK) , National Institutes of Health (NIH) , Bethesda, MD. The CRIC Study is supported by cooperative agreement project grants 5U01DK060990 , 5U01DK060984 , 5U01DK06102 , 5U01DK061021 , 5U01DK061028 , 5U01DK60980 , 5U01DK060963 , and 5U01DK060902 from the NIDDK, NIH .
PY - 2010/3
Y1 - 2010/3
N2 - Background: A low rate of blood pressure control has been reported in patients with chronic kidney disease (CKD). These data were derived from population-based samples with a low rate of CKD awareness. Study Design: Cross-sectional. Setting & Participants: Data from the baseline visit of the Chronic Renal Insufficiency Cohort (CRIC) Study (n = 3,612) were analyzed. Participants with an estimated glomerular filtration rate of 20-70 mL/min/1.73 m2 were identified from physician offices and review of laboratory databases. Outcomes: Prevalence and awareness of hypertension, treatment patterns, control rates, and factors associated with hypertension control. Measurements: Following a standardized protocol, blood pressure was measured 3 times by trained staff, and hypertension was defined as systolic blood pressure ≥140 mm Hg and/or diastolic blood pressure ≥90 mm Hg and/or self-reported antihypertensive medication use. Patients' awareness and treatment of hypertension were defined using self-report, and 2 levels of hypertension control were evaluated: systolic/diastolic blood pressure <140/90 and <130/80 mm Hg. Results: The prevalence of hypertension was 85.7%, and 98.9% of CRIC participants were aware of this diagnosis and 98.3% were treated with medications, whereas 67.1% and 46.1% had hypertension controlled to <140/90 and <130/80 mm Hg, respectively. Of CRIC participants with hypertension, 15%, 25%, 26%, and 32% were using 1, 2, 3, and ≥4 antihypertensive medications, respectively. After multivariable adjustment, older patients, blacks, and those with higher urinary albumin excretion were less likely, whereas participants using angiotensin-converting enzyme inhibitors and angiotensin receptor blockers were more likely to have controlled their hypertension to <140/90 and <130/80 mm Hg. Limitations: Data were derived from a single study visit. Conclusions: Despite almost universal hypertension awareness and treatment in this cohort of patients with CKD, rates of hypertension control were suboptimal.
AB - Background: A low rate of blood pressure control has been reported in patients with chronic kidney disease (CKD). These data were derived from population-based samples with a low rate of CKD awareness. Study Design: Cross-sectional. Setting & Participants: Data from the baseline visit of the Chronic Renal Insufficiency Cohort (CRIC) Study (n = 3,612) were analyzed. Participants with an estimated glomerular filtration rate of 20-70 mL/min/1.73 m2 were identified from physician offices and review of laboratory databases. Outcomes: Prevalence and awareness of hypertension, treatment patterns, control rates, and factors associated with hypertension control. Measurements: Following a standardized protocol, blood pressure was measured 3 times by trained staff, and hypertension was defined as systolic blood pressure ≥140 mm Hg and/or diastolic blood pressure ≥90 mm Hg and/or self-reported antihypertensive medication use. Patients' awareness and treatment of hypertension were defined using self-report, and 2 levels of hypertension control were evaluated: systolic/diastolic blood pressure <140/90 and <130/80 mm Hg. Results: The prevalence of hypertension was 85.7%, and 98.9% of CRIC participants were aware of this diagnosis and 98.3% were treated with medications, whereas 67.1% and 46.1% had hypertension controlled to <140/90 and <130/80 mm Hg, respectively. Of CRIC participants with hypertension, 15%, 25%, 26%, and 32% were using 1, 2, 3, and ≥4 antihypertensive medications, respectively. After multivariable adjustment, older patients, blacks, and those with higher urinary albumin excretion were less likely, whereas participants using angiotensin-converting enzyme inhibitors and angiotensin receptor blockers were more likely to have controlled their hypertension to <140/90 and <130/80 mm Hg. Limitations: Data were derived from a single study visit. Conclusions: Despite almost universal hypertension awareness and treatment in this cohort of patients with CKD, rates of hypertension control were suboptimal.
KW - Hypertension
KW - awareness
KW - chronic kidney disease
KW - control
KW - treatment
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U2 - 10.1053/j.ajkd.2009.09.014
DO - 10.1053/j.ajkd.2009.09.014
M3 - Article
C2 - 19962808
AN - SCOPUS:77049112022
SN - 0272-6386
VL - 55
SP - 441
EP - 451
JO - American Journal of Kidney Diseases
JF - American Journal of Kidney Diseases
IS - 3
ER -