Hyperpolarization of amino acid precursors to neurotransmitters with parahydrogen induced polarization

Pei Che Soon, Xiang Xu, Boyang Zhang, Francesca Gruppi, James W. Canary, Alexej Jerschow

Research output: Contribution to journalArticle

Abstract

Several important neurotransmitter precursors were hyperpolarized via homogeneous hydrogenation with parahydrogen. Polarization enhancement was achieved for 1H and 13C spins by several orders of magnitude compared to thermal spectra. Such large signal enhancements of these molecules could facilitate neurotransmitter studies.

Original languageEnglish (US)
Pages (from-to)5304-5306
Number of pages3
JournalChemical Communications
Volume49
Issue number46
DOIs
StatePublished - Jun 11 2013
Externally publishedYes

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Hydrogenation
Neurotransmitter Agents
Amino acids
Polarization
Amino Acids
Molecules
Hot Temperature

ASJC Scopus subject areas

  • Chemistry(all)
  • Catalysis
  • Ceramics and Composites
  • Electronic, Optical and Magnetic Materials
  • Surfaces, Coatings and Films
  • Materials Chemistry
  • Metals and Alloys

Cite this

Hyperpolarization of amino acid precursors to neurotransmitters with parahydrogen induced polarization. / Soon, Pei Che; Xu, Xiang; Zhang, Boyang; Gruppi, Francesca; Canary, James W.; Jerschow, Alexej.

In: Chemical Communications, Vol. 49, No. 46, 11.06.2013, p. 5304-5306.

Research output: Contribution to journalArticle

Soon, Pei Che ; Xu, Xiang ; Zhang, Boyang ; Gruppi, Francesca ; Canary, James W. ; Jerschow, Alexej. / Hyperpolarization of amino acid precursors to neurotransmitters with parahydrogen induced polarization. In: Chemical Communications. 2013 ; Vol. 49, No. 46. pp. 5304-5306.
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