Hyperplasia of the Myenteric Plexus

Its Association With Early Infantile Megacolon and Neurofibromatosis

Robert A. Saul, Raymond A. Sturner, Peter C. Burger

Research output: Contribution to journalArticle

Abstract

An infant with cutaneous criteria for neurofibromatosis had hyperplasia of the intestinal myenteric plexus and a clinical presentation mimicking Hirschsprung's disease. Many of his phenotypic features are also found in multiple endocrine neoplasia type IIb, a condition in which hyperplasia of the myenteric plexus is common. This case illustrates the overlapping nature of neural crest-derived conditions and the variable presentation of megacolon (ganglionic or aganglionic) in infancy.

Original languageEnglish (US)
Pages (from-to)852-854
Number of pages3
JournalAmerican Journal of Diseases of Children
Volume136
Issue number9
DOIs
StatePublished - 1982
Externally publishedYes

Fingerprint

Megacolon
Myenteric Plexus
Neurofibromatoses
Hyperplasia
Multiple Endocrine Neoplasia Type 2b
Hirschsprung Disease
Neural Crest
Skin

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

Cite this

Hyperplasia of the Myenteric Plexus : Its Association With Early Infantile Megacolon and Neurofibromatosis. / Saul, Robert A.; Sturner, Raymond A.; Burger, Peter C.

In: American Journal of Diseases of Children, Vol. 136, No. 9, 1982, p. 852-854.

Research output: Contribution to journalArticle

Saul, Robert A. ; Sturner, Raymond A. ; Burger, Peter C. / Hyperplasia of the Myenteric Plexus : Its Association With Early Infantile Megacolon and Neurofibromatosis. In: American Journal of Diseases of Children. 1982 ; Vol. 136, No. 9. pp. 852-854.
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