Abstract
Tight junctions between bovine brain capillary endothelial cells in primary cell culture are impermeable to horseradish peroxidase (HRP) after 5 min of incubation. However, following 1-5 min of exposure to 1.6 M arabinose, HRP penetrates the extracellular space between successive tight junctions. Endothelial cells in control cultures contain a small number of cytoplasmic pits and vesicles containing HRP which do not increase in number after hyperosmotic treatment.
Original language | English (US) |
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Pages (from-to) | 383-386 |
Number of pages | 4 |
Journal | Brain research |
Volume | 302 |
Issue number | 2 |
DOIs | |
State | Published - Jun 8 1984 |
Externally published | Yes |
Keywords
- arabinose
- brain capillary endothelium
- horseradish peroxidase
- tight junctions
ASJC Scopus subject areas
- Neuroscience(all)
- Molecular Biology
- Clinical Neurology
- Developmental Biology