Intra-amniotic hyperosmolar urea (59.7 per cent) augmented by intravenous oxytocin (332 mμ per minute), prostaglandin F(2α)(20 mg.), prostaglandin F(2α)(10 mg.), or prostaglandin F(2α)(5 mg.) was utilized for 1,913 patients requesting elective midtrimester abortion. Injection-abortion intervals ranging from 13.70 to 21.49 hours were achieved with failure rates of 0.7 to 6.7 per cent. Despite frequent pre-existing medical conditions, the complication rate compared favorably with those of other methods for terminating midtrimester pregnancy such as saline amnioinfusion or dilatation and evacuation.
ASJC Scopus subject areas
- Obstetrics and Gynecology